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Uric Acid and Renal Pathological Features

New Orleans—Patients with chronic kidney disease (CKD) commonly develop hyperuricemia, which increases the risk of cardiovascular events and accelerates CKD progression. Chinese researchers conducted a study to identify the relationship between baseline uric acid levels and renal pathological features. The study included 1070 patients who underwent renal biopsy at a single center. Of the 1070 patients, 429 were IgA nephropathy ... Read More »

ADPKD Patients with Advanced CKD at Increased Risk of Adverse Outcomes

New Orleans—Patients with autosomal dominant polycystic kidney disease (ADPKD) develop progressive chronic kidney disease (CKD) and a subsequent increased risk for adverse events that include cardiovascular disease, infections, end-stage renal disease (ESRD), and mortality. There are few data available on the risks of adverse events in patients with ADPKD and advanced CKD. Manish M. Sood, MD, and colleagues conducted a ... Read More »

Fluid Overload and AKI and Mortality in Influenza Patients

New Orleans—In a subset of critically ill patients with influenza, particularly A(H1N1), the influenza virus has been consistently associated with high mortality in patients who develop Acute Distress Respiratory Syndrome (ADRS).  There are few available data on the risk factors for this association. There have been studies documenting the association of fluid overload and an increase in the incidence of ... Read More »

Identifying Rapid Progression in Patients with ADPKD

New Orleans—The most frequently inherited kidney disease is autosomal dominant polycystic kidney disease (ADPKD). The progressive cyst growth associated with ADPKD, combined with interstitial damage, causes progressive kidney failure; there is wide variation of the severity of ADPKD among this patient population. The European Medicines Agency has approved tolvaptan for adults with CKD stage 1 to 3 at baseline who ... Read More »

Biomarkers for Early Diagnosis of AKI in Critically Ill Patients

New Orleans—Hospitalized patients may experience acute kidney injury (AKI), a condition that is more common among patients in the intensive care unit (ICU). Serum creatinine measurement can be used to assess AKI; however, according to Luana A. Pedroso, MD, and colleagues, serum creatinine is a poor and delayed marker of AKI. In recent decades, new circulating and urinary biomarkers have ... Read More »

Low to Moderate Alcohol Consumption Associated with Lower Risk of CKD

  The association of low to moderate consumption of alcohol with the risk of chronic kidney disease (CKD) has not been well studied. Previous longitudinal cohort studies examining the effect of alcohol consumption on the development of CKD have found mainly inverse associations; however, Some inconsistency exists. To further study this association, Sarah H. Koning, and colleagues recently analyzed data ... Read More »

Urgent-Start PD Preferred Modality for Appropriate Candidates

Urgent-Start PD Preferred Modality for Appropriate Candidates Dallas—Results from a recent single-center prospective cohort study suggest that urgent-start peritoneal dialysis (PD) should be the preferred modality of dialysis offered to appropriate PD candidates who present unplanned requiring urgent dialysis. The study was conducted by Neda Hashemi, MD, and colleagues and reported during a poster session at the NKF Spring Clinical ... Read More »

Test to Predict Sudden Cardiac death in Hemodialysis Patients

Researchers in Japan have developed a test to predict sudden cardiac death in hemodialysis patients. The test uses a combination of nuclear medicine, C-reactive protein, and electrocardiogram. Akiyoshi Hashimoto, MD, and colleagues reported results of the research at the International Conference on Nuclear Cardiology in Madrid, Spain, in May, according to an article in Medical News Today. “Hemodialysis patients are ... Read More »

NKF Holds Spring Clinical Meetings

The National Kidney Foundation held its 2015 Spring Clinical Meetings in Dallas, Texas, March 25-29. The meeting was an opportunity for renal health care providers to learn new developments related to all aspects of nephrology. It was designed for kidney doctors in the private sector and academia, fellows and residents with a special interest in kidney disease, general internists, pharmacists, ... Read More »

Anemia Risk Factor for AKI in Hospitalized Patients

Philadelphia—Anemia increases the risk of acute kidney injury (AKI) in hospitalized patients and the risk may be modified with correction of the anemia. Those were among the findings of research presented in a poster session during Kidney Week 2014 by Melanie Godin, MD, and colleagues. The poster was titled Anemia Is a Risk Factor for Development of Acute Kidney Injury ... Read More »