The National Kidney Foundation

Etelcalcetide Safe and Efficacious over 18 Months

Orlando—Researchers led by Sunfa Cheng, MD, recently conducted an analysis of data from a 52-week open label extension trial and an open label extension trial of up to 2.5 years of etelcalcetide, an intravenous calcimimetic that reduced secondary hyperparathyroidism in hemodialysis patients. The efficacy of etelcalcetide in reducing parathyroid hormone was demonstrated in three phase 3 trials. The researchers reported ... Read More »

Patiromer Safe and Effective Taken with or without Food

Orlando—Patiromer is a potassium binder approved by the US FDA for the treatment of hyperkalemia. The TOURMALINE study was designed to examine the efficacy and safety of once daily patiromer given with food compared with once daily patiromer given without food for the treatment of hyperkalemia. P.E. Pergola, MD, and colleagues reported results of the study during a poster session ... Read More »

Dietary Intake in Chronic Hemodialysis Patients Varies

Orlando—Patients with end-stage renal disease (ESRD) are at risk for impaired nutritional status. Ragda Barakat and colleagues in Israel recently conducted a cross-sectional study designed to evaluate dietary intake and quality, nutritional status, and indicators of ESRD in a cohort of patients on maintenance hemodialysis. The researchers reported study results during a poster session at the NFK Spring Clinical Meetings ... Read More »

Case Report: Refractory Hyponatremia in Malignant Melanoma

Orlando—There were approximately 76,000 new cases of malignant melanoma in the United States and 10,000 melanoma-related deaths in 2016. Some patients with malignant melanoma develop fungating wounds that are associated with significant patient distress and morbidity. Rui Mao, MD, and colleagues presented a case report on a 43-year-old man who developed malignant melanoma on his back with metastases to his ... Read More »

Data Update on Outcome of Long Duration CRRT

Orlando—More than 10 years ago, long duration of continuous renal replacement therapy (CRRT), defined as >4 weeks, was associated with a survival rate that was similar to shorter duration (43% vs 38%), according to a study conducted at Columbia University College of Physicians & Surgeons, New York, New York [Baird JS, Wald EL; Int J Artif Organs, 2010]. During a ... Read More »

Dietary Energy and Protein Intake and Nutrition-Specific Quality of Life

Orlando—To provide optimal nutrition in a population at risk for protein energy wasting, guidelines from the National Kidney Foundation Kidney Disease Outcomes Quality Initiative (KDOQI) recommend 30 to 35 calories per kilogram and 1.2 grams of protein per kilogram per day. Because of the relationship between morbidity and mortality, health-related quality of life is regularly assessed in patients on maintenance ... Read More »

Patient with Severe Hyponatremia and AKI: A Case Study

Orlando—According to Eddy DeJesus, MD, and colleagues, management of hyponatremia in the setting of acute kidney injury (AKI) is problematic. They presented the case study of a patient with severe hyponatremia in the setting of AKI requiring dialysis during a poster session at the NFK 2017 Spring Clinical Meetings in a poster titled A Case of Severe Hyponatremia and Acute ... Read More »

Serum Phosphorus Associated with Graft Failure and Mortality in Transplant Recipients

Orlando—Kidney transplant recipients may experience mild hyperphosphatemia, a risk factor for cardiovascular disease, loss of renal function, and mortality. There are few data available from large, multicenter cohorts of kidney transplant recipients examining the relationship between serum phosphorus and the development of cardiovascular outcomes, graft failure, or all-cause mortality among chronic, stable kidney transplant recipients. Basma Merhi, MD, and colleagues ... Read More »

Gastrointestinal Hemorrhage in Acute Kidney Injury Occurs Predominately in Men

Orlando—There are few epidemiological data available on the number of annual hospitalizations, variations in demographics, healthcare-related costs, and outcomes for patients with acute kidney injury (AKI) who experience gastrointestinal hemorrhage. Shantanu Solanki, MD, and colleagues recently conducted an analysis of data from the National Inpatient Sample (NIS) database to examine outcomes among that patient population. Results of the analysis were ... Read More »

Readmissions Reduced with Outpatient Provider Awareness of Inpatient Hyponatremia

Orlando—Hospitalized patients often experience hyponatremia, which is associated with increased risk of mortality. Previous studies have demonstrated the prognostic significance of hyponatremia; however, outpatient providers are often not informed of a hyponatremia diagnosis upon hospital discharge. Researchers, led by Gordon J. Hildick-Smith, BA, conducted a retrospective cohort study designed to examine the association of communicating inpatient hyponatremia to outpatient providers ... Read More »