Online Exclusives

Sodium Bicarbonate Reduces Inter-Hemodialysis Potassium Gain

Chicago—One of the adverse effects of hemodialysis on clinical outcomes is associated with the intermittent nature of the therapy; increased mortality rates are related to long intervals between sessions. One reason for adverse effects of long intervals between therapy is high levels of potassium, however, according to researchers in the United Kingdom, low potassium levels post-hemodialysis can cause arrhythmias. Stella ... Read More »

Factors Associated with Home Hemodialysis Use and Discontinuation

Boston—Compared with patients who receive hemodialysis in a dialysis center, those who undergo home hemodialysis have more time on dialysis and experience better outcomes, including quality of life, blood pressure control, mineral metabolism, fewer cardiovascular-related hospitalizations, and overall survival. However, currently fewer than 2% of dialysis patients in the United States use home hemodialysis. Possible factors contributing to the low ... Read More »

Hyponatremia Associated with Osteoporosis and Fracture

Boston—Previous studies have shown an association between hyponatremia, a common electrolyte disorder, and osteoporosis and bone fracture. However, according to Anawin Sanguankeo, MD, and colleagues, there are few data clarifying whether hyponatremia directly associates with osteoporosis and fracture or if it is a surrogate marker of other causes. The researchers conducted a systematic review and meta-analysis of observational studies designed ... Read More »

Include Adrenal Insufficiency in Differential for Hyponatremia

Boston—Patients with hyponatremia due to adrenal insufficiency usually present with hypotension, hyperkalemia, hypercalcemia, and hypoglycemia. Patients with SIADH (syndrome of inappropriate antidiuretic hormone secretion) are euvolemic and normotensive. During a poster session at the NKF Spring Clinical Meetings, Avantika Chenna, MD, and colleagues described a case history of a patient with hyponatremia due to adrenal insufficiency who presented without the ... Read More »

Hospital to Home Transition for Patients with CKD and Acute Heart Failure

Boston—Hospitalization for acute heart failure is common and the risk of rehospitalization is increased in patients with chronic kidney disease (CKD). Paul Drawz, MD, MHS, MS, and colleagues conducted an evaluation of medication use and care processes during the transition from inpatient to outpatient care in a population of patient with CKD who were hospitalized for chronic heart failure. The ... Read More »