DASH Diet May Offer Protection Against Kidney Disease

Multiple clinical guidelines recommend the DASH (Dietary Approaches to Stop Hypertension) diet for the promotion of good health and prevention of disease. DASH includes a dietary pattern high in fruits, vegetables, and dairy products that are low in fat. Reducing sodium intake further lowers blood pressure and reduces the risk for hypertension, type 2 diabetes, cardiovascular disease, stroke, and mortality. ... Read More »

No Differences in Measured GFR Between Blacks and Whites

Ethnic and minority groups in the United States shoulder a disproportionate burden of chronic kidney failure; incidence rates for treatment of kidney failure by dialysis and transplantation are approximately three times higher in older blacks compared with whites. There are no conclusive data on the cause of the higher incidence of kidney failure in blacks compared with whites; however, community-based ... Read More »

Patients with Elevated C-Reactive Protein at Increased Risk for ESRD

Of adults with self-reported diabetes in the United States, 40% are affected by chronic kidney disease (CKD). For CKD patients, diabetes is a major risk factor for progression of CKD; it is the leading cause of end-stage renal disease (ESRD), associated with approximately 50,000 new cases in 2012 alone. In patients with and without a history of cardiovascular events and ... Read More »

Cell Cycle Arrest Biomarkers Predict Risk of AKI

Acute kidney injury (AKI) occurs in as many as 20% of hospitalized patients; AKI is associated with high morbidity and mortality. A key component of management of patients with AKI is limiting further renal damage when injury occurs. Early diagnosis and recognition of AKI can attenuate ongoing injury. In patients with underlying chronic conditions, it can be challenging to identify ... Read More »

CRIC Study Analysis: No Significant Racial/Ethnic Differences in Risk for Cardiovascular Outcomes

The risks for cardiovascular disease, cardiovascular mortality, and all-cause mortality are all increased in the presence of chronic kidney disease (CKD), yet reasons for the high burden of cardiovascular disease among patients with CKD are unclear. Patients with CKD experience a high prevalence of traditional and nontraditional cardiovascular risk factors that likely play a key role in the pathogenesis of ... Read More »

April 2017: Abstract Roundup

Acute Kidney Injury Algorithm Assists RRT Initiation Timing Decision Making Clinical Journal of the American Society of Nephrology. 2017;12(2):228-236 Severe acute kidney injury (AKI) that requires renal replacement therapy is associated with a >40% in-hospital mortality rate. There are no standardized recommendations related to clinical decision making regarding initiation of renal replacement therapy for patients with AKI in the medical ... Read More »

April 2017: News Briefs

Bipartisan Bill to Protect Living Organ Donors Introduced In early March, Representative Jerrold Nadler (D-NY) and Representative Jaime Herrera Beutler (R-WA) introduced the Living Donor Protection Act of 2017. The bill is intended to protect the rights of living organ donors, according to a press release from Mr. Nadler’s office. The act includes three mechanisms to protect donors: (1) prohibition ... Read More »

March 2017: Abstract Roundup

Acute Kidney Injury  AKI Associated with Long-Term Risk for Cardiovascular Events Journal of the American Society of Nephrology. 2017;28(1):377-387 In a study designed to determine whether there is an association between acute kidney injury (AKI) and long-term cardiovascular disease, Ayodele Odutayo, MD, and colleagues performed a systematic review and meta-analysis of previous cohort studies. The studies of interest included adults ... Read More »

March 2017: News Briefs

Real-Time Models Predict Risk of AKI In a study conducted recently among acute kidney injury (AKI) patients at the University of Pennsylvania Hospital in Philadelphia, researchers found that measuring and accounting for risk factors in real-time worked well for predicting dialysis, death, and length of stay. The strategy worked well whether using a traditional logistic regression model or machine-learning techniques. ... Read More »

Patient and Graft Survival Rates in Octogenarians Undergoing Kidney Transplantation

Worldwide, the population is aging, leading to an increase in the number of individuals with chronic disease, including an increasing prevalence of older patients with end-stage renal disease (ESRD). The preferred treatment for patients with ESRD is kidney transplantation, which is relatively safe and provides survival advantage over dialysis for the majority of patients. Previous studies have demonstrated acceptable outcomes ... Read More »