Slowing Progression and Treating Blood Pressure in ADPKD Patients?

  Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic kidney disease and accounts for approximately 10% of all patients currently on dialysis in the United States. It is characterized by a relentless growth of cysts in the kidney that ultimately leads to kidney failure in almost all patients. The optimal blood pressure target to slow progression of ... Read More »

Recovery Time Related to Quality of Life and Mortality in Hemodialysis Patients

Patients with poor health-related quality of life (HRQoL) and high risk of hospitalization and mortality can be identified using patient-reported recovery time. That was the primary finding of a prospective cohort study conducted by Hugh C. Rayner, MD, FRCP, and colleagues. The researchers reported results in the American Journal of Kidney Diseases [2014.64(1):86-94]. HRQoL is impacted to a great degree ... Read More »

CKD and Potentially Preventable Hospitalizations

    Prevention of ambulatory care-sensitive conditions (ACSCs) specific to chronic kidney disease (CKD) should target patients living remotely from healthcare providers and those with certain comorbid conditions. That was the main finding of a retrospective cohort study conducted by Natasha Wiebe and colleagues. Study results were reported in the American Journal of Kidney Diseases [2014;64(2):230-238]. It is well documented that ... Read More »

Simple Model Is Best Predictor of Renal Scarring in Children with UTI

Children and adolescents with an abnormal renal ultrasonographic finding or with a combination of fever ≥39° C and an etiologic organism (other than Escherichia coli [E coli]) are at high risk for the development of renal scarring. That was among the findings of a meta-analysis conducted recently by Nader Smith, MD, MPH, and colleagues and reported online in JAMA Pediatrics ... Read More »

SBP Visit-to-Visit Variability Associated with Kidney Disease Outcomes

There is an independent association between variability visit-to-visit in systolic blood pressure (SBP) and hard kidney disease outcomes in diabetic patients with nephropathy. That was the primary finding of an observational analysis conducted recently by Ciaran J. McMullan, MD, MMSc, and colleagues. The researchers reported their findings in the American Journal of Kidney Diseases [2014;64(5):714-722]. It has been demonstrated that ... Read More »

Suprises On The Horizon

SUPRISES ON THE HORIZON At this time last year, nephrologists and the rest of those in healthcare were nervous and anxious about the implementation of the International Classification of Diseases, Tenth Edition (ICD-10). After the 1 year delay was implemented, many in healthcare seem to have become bored with ICD-10 and have few worries about it, even though its implementation ... Read More »

Little Victories

Kenneth A. Liss, DO- In the last edition of this journal, Dr. Singh referenced some troubling statistics that many of us in the nephrologic community are already keenly aware.1 Simply,  the chronic kidney disease population rapidly grows while the number of quality healthcare professionals able to provide care plummets. In order to attract both the “best and the brightest,” Dr. ... Read More »

Outcomes in Elderly CKD Patients Managed without Dialysis

Survival of elderly patients who choose to forego dialysis was a median of 16 months in a prospective observational study conducted recently by Mark A. Brown, MD, and colleagues. The study was designed to examine survival, symptom burden, and quality of life in a cohort of elderly patients with advanced chronic kidney disease managed without dialysis. Outcomes in a group ... Read More »

Alcohol Consumption and Risk for CKD

In a population-based cohort, there was an inverse association between alcohol consumption and the risk of developing chronic kidney disease (CKD). Noting that there are few data on the associations between consumption of alcohol and the risk of CKD, Sarah H. Kroning, MD, and colleagues conducted a prospective study of 5476 participants in the PREVEND (Prevention of Renal and Vascular ... Read More »

Estimating GFR in Pediatric Transplant Recipients

The Chronic Kidney Disease in Children (CKiD) 2012 formula had the best performance in assessing renal function in pediatric kidney transplant recipients, according to results of a study conducted by Vandrea de Souza, MD, et al. The most commonly used formulas to predict glomerular filtration rate (GFR) in this population are plasma creatinine (PCr)-based or cystatin C (CystC)-based. However, according ... Read More »