Obesity and High BP Risks for Microalbuminuria

Among relatives of patients with type 2 diabetes and diabetic nephrology, the main predictive risk factor of diabetic nephropathy in healthy subjects was obesity and/or high blood pressure in synergism with high-sensitivity C-reactive protein and high density lipoprotein cholesterol levels. The cross-sectional study, conducted by Graciela Zambrano-Galván, PhD and colleagues, included subjects aged 18 to 63 years with body mass ... Read More »

Statin Therapy and AF in ESRD Patients

Statin therapy was associated with lower risk of newly diagnosed atrial fibrillation (AF) in patients receiving dialysis as treatment of end-stage renal disease (ESRD). That was the primary finding of a study conducted recently by Li-Ting Ho, MD, and colleagues. The researchers utilized a database from the Registry for Catastrophic Illness from the National Health Research Institute, which encompasses nearly ... Read More »

CIED-Related Infections in Hemodialysis Patients

Hemodialysis patients with infections associated with cardiovascular implantable electronic devices (CIED) have a high risk of mortality. The risk remains despite the complete removal of the device. That was the major finding of a case series study conducted recently by LaTonya J. Hickson, MD, and colleagues. Study results were reported in the American Journal of Kidney Diseases [2014;64(1):104-110]. Kidney failure ... Read More »

Guiding Fluid Management Using Bioimpedance-Based Technologies

There were improvements in both surrogate and hard end points following strict volume control using bioimpedance to guide dry weight adjustment in a recent study conducted by Mihai Onofriescu, MD, and colleagues. The randomized controlled parallel-group trial was designed to compare strict volume control based on bioimpedance versus clinical methods for guiding ultrafiltration prescription in patients receiving hemodialysis (HD). The ... Read More »

Off-Pump vs On-Pump CABG Surgery and Subsequent Kidney Function

“The findings from this study emphasize that proof is needed to claim an intervention that reduces the risk of mild acute kidney injury better preserves long-term kidney function for the group that received it. This has implications for the development, testing, and use of interventions designed solely to prevent the degrees of acute kidney injury observed in CORONARY, and in ... Read More »

Elevated Albuminuria Associated with Incident Hypertension

Pathogenesis and Treatment of Kidney Disease American Journal of Kidney Diseases. 2015; 65(1):58-66. All kidney makers were associated with prevalent hypertension, but only elevated albuminuria was consistently associated with incident hypertension in the ARIC (Atherosclerosis Risk in Communities) study. Minxuan Huang, ScM, and colleagues reported results of the study designed to investigate several markers of kidney function and their association ... Read More »

Sevelamer versus Calcium Acetate in Elderly Hemodialysis Patients

Compared with treatment with calcium acetate, treatment with sevelamer for managing hyperphosphatemia in elderly incident hemodialysis patients was associated with similar or slightly lower risk of death and similar risk of hospitalization. Those were the main findings of an observational cohort study conducted recently by Akeem A. Yusuf, PhD, and colleagues. The researchers utilized the US Renal Data System data ... Read More »

The Nephrology Workforce Crisis

It is not an exaggeration to say that nephrology is in the midst of a workforce crisis. According to two surveys commissioned by the American Society of Nephrology (ASN) and recently published on its website,1,2  there has been a steep increase in the number of unfilled US nephrology training programs: In 2010, there were 15 unfilled programs (10.6% of 142), ... Read More »

Relative Energy Intake and Mortality in CKD Patients

There was an association with increased all-cause mortality in patients with estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m2 and increasing relative energy intake. That was the major finding of a prospective cohort study conducted recently by Samuel Iff, MD, and colleagues. Previous studies have demonstrated that death from events related to cardiovascular disease increased inversely with decreasing eGFR; patients ... Read More »

ACEi/ARB Use and AKI-D after Major Surgery

Preoperative use of an angiotensin converting enzyme inhibitor (ACEi) or angiotensin receptor blocker (ARB) was associated with a lower risk of acute kidney injury treated with dialysis (AKI-D) compared with nonuse. That was one of the findings of a large population-based retrospective cohort study conducted by Mitesh Shah, MBBS, MSc, and colleagues. The researchers reported study results in BMC Nephrology ... Read More »