Outcomes in Elderly CKD Patients Managed without Dialysis

Survival of elderly patients who choose to forego dialysis was a median of 16 months in a prospective observational study conducted recently by Mark A. Brown, MD, and colleagues. The study was designed to examine survival, symptom burden, and quality of life in a cohort of elderly patients with advanced chronic kidney disease managed without dialysis. Outcomes in a group ... Read More »

Alcohol Consumption and Risk for CKD

In a population-based cohort, there was an inverse association between alcohol consumption and the risk of developing chronic kidney disease (CKD). Noting that there are few data on the associations between consumption of alcohol and the risk of CKD, Sarah H. Kroning, MD, and colleagues conducted a prospective study of 5476 participants in the PREVEND (Prevention of Renal and Vascular ... Read More »

Estimating GFR in Pediatric Transplant Recipients

The Chronic Kidney Disease in Children (CKiD) 2012 formula had the best performance in assessing renal function in pediatric kidney transplant recipients, according to results of a study conducted by Vandrea de Souza, MD, et al. The most commonly used formulas to predict glomerular filtration rate (GFR) in this population are plasma creatinine (PCr)-based or cystatin C (CystC)-based. However, according ... Read More »

Trends in Living Donation Tied to Household Income

There is a decline in the rate of living kidney donation in the United States. Jagbir Gill, MD, and colleagues recently conducted a study designed to examine longitudinal trends in living donation as a function of median household income and donor relation. The researchers aimed to determine the effect of financial barriers on donation in a changing economic environment. The ... Read More »

Renal Sonography as Tool for Assessment of CKD

Improving the degree of correlation of renal sonography with glomerular filtration rate (GFR) makes renal sonography a reliable tool for assessment of patients with chronic kidney disease. That was among the findings of a cross-sectional study conducted recently by Geatano Lucisano, MD, et al. The study was designed to test the hypothesis that if “conventionally measured renal sonographic parameters are ... Read More »

New-Onset AF in Patients with ESRD

Patients with end-stage renal disease (ESRD) have a significantly higher risk of new-onset atrial fibrillation (AF) compared with those without ESRD, according to results of a study conducted by Jo-Nan Liao, MD, and colleagues. AF, which is prevalent in patients with ESRD, has a negative impact on patient outcomes. This study was designed to assess the incidence and risk factors ... Read More »

Obesity and High BP Risks for Microalbuminuria

Among relatives of patients with type 2 diabetes and diabetic nephrology, the main predictive risk factor of diabetic nephropathy in healthy subjects was obesity and/or high blood pressure in synergism with high-sensitivity C-reactive protein and high density lipoprotein cholesterol levels. The cross-sectional study, conducted by Graciela Zambrano-Galván, PhD and colleagues, included subjects aged 18 to 63 years with body mass ... Read More »

Statin Therapy and AF in ESRD Patients

Statin therapy was associated with lower risk of newly diagnosed atrial fibrillation (AF) in patients receiving dialysis as treatment of end-stage renal disease (ESRD). That was the primary finding of a study conducted recently by Li-Ting Ho, MD, and colleagues. The researchers utilized a database from the Registry for Catastrophic Illness from the National Health Research Institute, which encompasses nearly ... Read More »

CIED-Related Infections in Hemodialysis Patients

Hemodialysis patients with infections associated with cardiovascular implantable electronic devices (CIED) have a high risk of mortality. The risk remains despite the complete removal of the device. That was the major finding of a case series study conducted recently by LaTonya J. Hickson, MD, and colleagues. Study results were reported in the American Journal of Kidney Diseases [2014;64(1):104-110]. Kidney failure ... Read More »

Guiding Fluid Management Using Bioimpedance-Based Technologies

There were improvements in both surrogate and hard end points following strict volume control using bioimpedance to guide dry weight adjustment in a recent study conducted by Mihai Onofriescu, MD, and colleagues. The randomized controlled parallel-group trial was designed to compare strict volume control based on bioimpedance versus clinical methods for guiding ultrafiltration prescription in patients receiving hemodialysis (HD). The ... Read More »