News

Kidney Function and Survival in Older Patients after Rehabilitation Stay

In older patients discharged from inpatient rehabilitation, estimated glomerular filtration rate (eGFR) category and Barthel score are independent risk factors for survival; however, advanced chronic kidney disease (CKD) does not preclude successful rehabilitation. That was among the findings of an analysis conduced recently by Edward M. Doyle and colleagues reported in the American Journal of Kidney Diseases [2015;66(50:768-774]. With advancing ... Read More »

Causes of Death in Patients with CKD and Diabetes in TREAT

Lower baseline glomerular filtration rate (GFR) and higher protein-creatinine ratio (PCR) were associated with both higher cardiovascular (CV) and non-CV mortality rates. That finding, from a study conducted recently, was particularly significant in cases of sudden death and in infection-related mortality. David M. Charytan, MD, MSc, and colleagues reported results of the retrospective analysis of data from a prospective randomized ... Read More »

Lower eGFRs and higher ACRs Associated with Higher Risks of AKI

In a recent meta-analysis, researchers found that among individuals with or without either diabetes mellitus or hypertension, lower estimated glomerular filtration rates (eGFRs) and high albuminuria are associated with higher risks of acute kidney injury (AKI). Matthew T. James, MD, PhD, and colleagues reported results of the analysis in the American Journal of Kidney Diseases [2015;666(4):602-612]. The incidence of AKI ... Read More »

Increased Albuminuria and Reduced eGFR Associated with Risk of AKI

Stratification of the risk of acute kidney injury (AKI) by kidney measures, such as estimated glomerular filtration rate (eGFR) and albumin-creatinine ratio (ACR), may be more useful than factors such as age, sex, or race. That was the primary finding of a collaborative meta-analysis performed recently by Morgan E. Grams, MD, PhD, and colleagues. The researchers reported their findings in ... Read More »

November/December 2015 News Briefs

CVInsight™ Used in Dialysis Centers in Ohio The largest provider of dialysis care in northeast Ohio, the Centers for Dialysis Care (CDC), has implemented use of next-generation, non-invasive cardiovascular monitoring in its centers in the state. CDC has entered into a multiyear contract with InteloMed, Inc., that allows for the deployment of the CVInsight™ to CDC facilities system-wide over the ... Read More »

Use of PPIs and Concentration of Serum Mg in Hemodialysis Patients

Among patients on hemodialysis, compared with nonusers, patients who use proton-pump inhibitors (PPIs) have lower serum magnesium (Mg) levels. That was the primary finding of a study conducted recently by Paraish S. Misra, MD, and colleagues. Study results were reported in BMC Nephrology [2015, doi:19.1186/s12882-015-0139-9]. Data from previous observational studies suggest that Mg concentration is inversely related to vascular calcification ... Read More »

Renal Blood Flow and Oxygenation in Patients with CKD

A larger reduction of measured glomerular filtration rate (mGFR) than renal artery blood flow is characteristic in people with stable chronic kidney disease (CKD) stages 3 to 4. That was among the findings of a cross-sectional study conducted recently by Dinah S. Khartir, MD, PhD, and colleagues. Study results were reported in the American Journal of Kidney Diseases [2015;66(3):402-411]. According ... Read More »

Low Medication Adherence Associated with Adverse Safety Events

In those with estimated glomerular filtration rates (eGFRs) <60 mL/min/1.73 m2, there is an association between lower medication adherence and adverse safety events. That was the primary finding of a cross-sectional baseline analysis of a prospective cohort conducted by Kailin L. Hsu, BS, and colleagues. The researchers reported results of the analysis in the American Journal of Kidney Diseases [2015;66(4):621-629]. ... Read More »

Finerenone Improves the Urinary Albumin-Creatinine Ratio in Patients with Diabetic Nephropathy

In patients with diabetic nephropathy, most receiving an angiotensin-converting enzyme (ACE) inhibitor or an angiotensin receptor blocker (ARB), there was improvement in the urinary albumin-creatinine ratio with the addition of finerenone compared with placebo. That was the primary finding of a randomized, double-blind, placebo-controlled, parallel-group study conducted by George L. Bakris, MD, and colleagues. The researchers reported their findings in ... Read More »

Dental Health and Mortality in Patients with End-Stage Kidney Disease

Patients with chronic kidney disease (CKD) experience more extensive dental disease compared with individuals in the general population. It is unknown, however, whether dental health and behaviors are associated with survival among patients with end-stage renal disease receiving hemodialysis. Suetonia C. Palmer, PhD, and colleagues recently conducted the Oral-D (Oral Disease in Hemodialysis) Study to examine whether disease using standardized ... Read More »