Dialysate Potassium Level and Adverse Events in Patients on Hemodialysis

In patients requiring hemodialysis, sudden death is a leading cause of death; 27% of all deaths in that patient population are attributable to arrhythmic mechanisms. In patients on maintenance hemodialysis three times a week, these events tend to cluster in the period just prior to the first dialysis session of the week when fluid overload and levels of various uremic ... Read More »

Treating Children and Adolescents with ESRD: A Guide for Nephrologists

It is rare for children to be diagnosed with end-stage renal disease (ESRD); there are approximately 8500 children with ESRD in the United States, according to the most recent US Renal Data System report. Each year, approximately 1500 children in the United States develop ESRD; two-thirds of those patients initiate treatment with hemodialysis and one-third initiate treatment with peritoneal dialysis. ... Read More »

July/August 2017: Abstract Roundup

CHRONIC KIDNEY DISEASE Benefits of Phosphorus Binder Use among Non-Dialysis CKD Patients American Journal of Nephrology. 2017;45(5);431-441. It is unknown whether the benefits of phosphorus binders extend to patients with chronic kidney disease (CKD) but without end-stage renal disease. In a retrospective cohort study conducted by Simran Bhandari, MD, and colleagues, the researchers sought to evaluate phosphorus binder use and ... Read More »

July/August 2017: News Briefs

KDIGO Issues Updated Guidelines for Treatment of CKD-MBD In late June, the Kidney Disease Improving Global Outcomes (KDIGO) updated its Practice Guideline for the Diagnosis, Evaluation, Prevention, and Treatment of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD). The update amends the 2009 KDIGO Clinical Practice Guideline and includes revised positions on standards of care for the treatment of secondary hyperparathyroidism ... Read More »

CMS Reimbursement Reform and Hospitalizations and Readmissions among Hemodialysis Patients

Many healthcare reforms rely on pay-for-performance (P4P) initiatives. In P4P models, quality of care affects the reimbursement received by the provider. Quality of care is determined by either deliver-of-care processes deemed important or achieving specific health outcomes. Recent P4P initiatives that target care processes include Centers for Medicare & Medicaid (CMS) programs that pay for transitional care management and long-term ... Read More »

Fluid Overload in AKI Patients Receiving Continuous Renal Replacement Therapy

Critically ill patients often experience acute kidney injury (AKI), which despite advances in intensive care medicine, has poor prognosis. Patients with AKI are at significant risk for morbidity and mortality. Among patients with AKI, approximately 4% require renal replacement therapy and may receive continuous renal replacement therapy (CRRT) to achieve hemodynamic stability. A mainstay of management of critically ill patients ... Read More »

Dietary Intervention to Reduce Vasopressin Secretion in ADPKD Patients

An estimated eight to ten percent of patients in the United States and Europe with end-stage renal disease (ESRD) are also affected by autosomal dominant polycystic kidney disease (ADPKD). At present, there are no treatments to prevent the development of ESRD in patients with ADPKD. Compared with healthy controls, ADPKD patients have impaired urine-concentrating ability and higher levels of arginine ... Read More »

May/June 2017: Abstract Roundup

Acute Kidney Injury Prepregnancy AKI Associated with Adverse Outcomes in Pregnancy Journal of the American Society of Nephrology. 2017;28(5):1566-1574 There are few data available on the effect of clinically recovered acute kidney injury (AKI) on future pregnancy outcomes. Jessica Sheehan Tangren, MD, and colleagues retrospectively studied all women who delivered infants between 1998 and 2007 at Massachusetts General Hospital. The ... Read More »

May/June 2017: News Briefs

Fresenius and Humana Announce Model of Care Coordination Fresenius Medical North American (FMCNA) is joining forces with Humana Inc. in a program designed to improve care and outcomes for Humana’s members with end-stage renal disease. FMCNA, operating through its Fresenius Health Partners mantle, will apply its proprietary model of care coordination aimed at enhancing the ability of patients to obtain ... Read More »

DASH Diet May Offer Protection Against Kidney Disease

Multiple clinical guidelines recommend the DASH (Dietary Approaches to Stop Hypertension) diet for the promotion of good health and prevention of disease. DASH includes a dietary pattern high in fruits, vegetables, and dairy products that are low in fat. Reducing sodium intake further lowers blood pressure and reduces the risk for hypertension, type 2 diabetes, cardiovascular disease, stroke, and mortality. ... Read More »