KDIGO CKD Referral Guidelines: Feasibility of Adherence

Early referral of patients with chronic kidney disease (CKD) to specialist nephrology care is associated with benefits that include reduced mortality at 3 months to 5 years of follow-up, reduced costs, reduced length of stay among hospitalized patients, increased quality of life, and earlier placement of preferred dialysis access. One objective of the US Office of Disease Prevention and Health ... Read More »

CRRTnet: Observational Study of Prescription and Delivery of Continuous Renal Replacement Therapy

More than half of admission to the intensive care unit (ICU) are complicated by acute kidney injury (AKI), and approximately 5% to 6% of patients admitted to the ICU require renal replacement therapy (RRT). Among patients with hemodynamic instability, continuous RRT (CRRT) is the dialysis modality of choice in high-income nations. According to Michael Heung, MD, MS, and colleagues, there ... Read More »

Early Frequent Nephrology Care Reduces Cardiovascular Risk Factors Postdialysis

Compared with age-matched controls, patients with chronic kidney disease (CKD) face a 5- to 10-fold higher risk for cardiovascular disease, including coronary artery disease, stroke, and heart failure. Cardiovascular events are the leading cause of death in patients with CKD. Interventions aimed at controlling traditional risk factors for cardiovascular disease (hypertension, diabetes, and dyslipidemia) were not associated with improvement in ... Read More »

October 2017: Abstract Roundup

Acute Kidney Injury 30-Day Outcomes Poor Following Discharge from the ED with AKI Clinical Journal of the American Nephrology Society. 2017, doi: 10.2215/CJN.10431016 Rey R. Acedillo, MD, and colleagues conducted a population-based retrospective cohort study designed to examine the characteristics and outcomes of patients discharged home from an emergency department (ED) with acute kidney injury (AKI). The cohort included 6346 ... Read More »

October 2017: News Briefs

LUTONIX® 035 DCB Granted FDA Approval In late August, the US FDA granted premarket approval to the LUTONIX® 035 drug coated balloon (DCB) PTA catheter. The LUTONIX 035 is now available in the United States. In a press release from C.R. Bard, Inc., the manufacturer of the catheter, Timothy M. Ring, chairman and chief executive officer, said, “This approval offers ... Read More »

Review and Meta-Analysis to Assess Renal Outcomes with Intensive Blood Pressure Control

Patients with chronic kidney disease face increased risk of diabetes, cardiovascular morbidity, and mortality; nondiabetic CKD accounts for most of the incidence worldwide. Hypertension is strongly associated with the development of progression of nondiabetic CKD, and control of blood pressure can decrease the risk of decline in renal function and cardiovascular mortality. However, according to Wan-Chuan Tsai, MD, and colleagues ... Read More »

Three versus Four Daily Exchanges in Continuous Ambulatory Peritoneal Dialysis and Residual Kidney Function

Survival and quality of life for patients on dialysis are associated with residual kidney function. The preferred modality for preservation of residual kidney function is peritoneal dialysis, according to Hao Yan, MD, and colleagues in the department of nephrology, Renji Hospital, School of Medicine, Shanghai Jiaotong University and Shanghai Center for Peritoneal Dialysis Research, Shanghai, China. The preservation of residual ... Read More »

Peritoneal Dialysis Compared with Hemodialysis in Infants Younger than One Year

Pediatric nephrologists face significant challenges in managing infants requiring maintenance dialysis. Factors such as difficulties feeding and maintaining fluid balance, growth failure, increased risk of infection, and possible comorbid conditions contribute to the management hurdles in children younger than 1 year. Due in part to these challenges, infants with kidney failure on maintenance dialysis have higher mortality rates than older ... Read More »

Appropriateness of Antibiotics Prescribed to Hemodialysis Patients

Worldwide, mortality and hospitalization in patients receiving maintenance hemodialysis are due, in part, to infection. Individuals in this patient population are also at risk of infections caused by multi-drug resistant organisms. Inappropriate use of antibiotics is a driver for the acceleration of antimicrobial resistance, giving rise to global efforts to optimize antimicrobial use. Patients in Australia receive maintenance hemodialysis in ... Read More »

Fall Injury Risk in Older Adults Increases after Dialysis Therapy Initiation

Among community-dwelling older adults, falls are the leading cause of injury-related hospitalizations and may lead to disability and death. More than one in three older adults fall each year, and nearly half of those falls result in injury. Earlier studies have demonstrated that serious fall injuries commonly occur among older adults with chronic kidney disease (CKD); higher levels of albuminuria ... Read More »