January/February 2017: Abstract Roundup

Chronic Kidney Disease Coffee Consumption and Risk of CKD International Journal of Clinical Practice. doi: 10.1111/ijcp.12919 Researchers, led by Karn Wijarnpreecha, MD, conducted a literature search and meta-analysis to assess the association between consumption of coffee and chronic kidney disease (CKD). The literature search included MEDLINE, EMBASE, and Cochrane Database of Systematic Reviews from inception to April 2016. Included studies ... Read More »

January/February 2017: News Briefs

Rapid Withdrawal of Steroids Reduces Incidence of Diabetes Post-Transplant Initiation of rapid withdrawal from steroids can reduce the incidence of diabetes after a kidney transplant in immunologically low-risk patients, according to research presented during Kidney Week 2016 by Christian Hugo, MD and colleagues. The research was cited in an article in Medpage Today. The researchers conducted a study among 587 ... Read More »

Prediabetes a Risk Factor for Glomerular Hyperfiltration

Diabetes-related kidney disease accounts for nearly half of the adults in the United States with end-stage renal disease (ESRD). Among patients with new-onset diabetes, a large percentage will develop chronic kidney disease (CKD). Prediabetes affects 20% to 35% of adults, and it progresses to diabetes in 445% to 50% of patients after 10 years. Cross-sectional studies have shown an association ... Read More »

Renal Implications of the EMPA-REG OUTCOME Trial

Patients with type 2 diabetes are at increased risk for macrovascular and microvascular disease. Approximately 35% of patients with type 2 diabetes develop kidney disease, which is associated with increased mortality. Surrogate markers of renal complications have been reduced with intensive glucose-lowering strategies in patients with type 2 diabetes; however, there are few data on the evidence for improvement in ... Read More »

Folic Acid in Combination with Enalapril Delays CKD Progression

Chronic kidney disease (CKD) leads to poor outcomes and high healthcare costs. CKD increases the risk of progression to end-stage renal disease (ESRD) and cardiovascular disease. The mainstay of treatment to delay decline in renal function is antihypertensive therapy, with an emphasis on the inhibition of the renin-angiotensin system. However, the number of patients requiring renal replacement therapy continues to ... Read More »

Pain and Decline in Kidney Function and Risk of Mortality

Chronic nonmalignant pain affects nearly 100 million people in the United States, accounting for 20% of outpatient visits, 12% of all prescriptions, and >$100 billion per year of direct and indirect costs. Chronic pain is more common in individuals with comorbid conditions such as cardiovascular disease, diabetes mellitus, and hypertension. Chronic kidney disease (CKD) is a frequent consequence of those ... Read More »

No Change in Prevalence of Diabetic Kidney Disease Since 1988

There have been increases in the prevalence of both diabetes mellitus and diabetic kidney disease (DKD) over the past 20 years. Worldwide, the most common cause of kidney disease is diabetes, leading to complications that include end-stage renal disease, cardiovascular disease, infection, and death. The clinical manifestations of chronic kidney disease in the setting of diabetes or DKD are albuminuria, ... Read More »

November/December 2016: News Briefs

CMS Announces Dialysis Facility Compare Five-Star Ratings System Results Satellite Healthcare Recognized by CMS Five-Star Ratings System Satellite Healthcare has been identified by the Centers for Medicare & Medicaid Services (CMS) Five-Star Quality Rating System as having the highest percentage of top-rated dialysis centers of the ten largest national dialysis providers. In a press release from Satellite, Brigitte Schiller, MD, ... Read More »

October 2016: News Briefs

Analysis of Secondary Data on Patiromer Results of a pre-specified exploratory analysis of data from the phase 3 OPAL-HK trial of Veltassa® (patiromer) for oral suspension were reported online in Kidney International. Results of the newly published analysis demonstrated that patients taking patiromer had significant decreases in systolic and diastolic blood pressure and reduced levels of aldosterone in the blood. ... Read More »

Aspirin Use Not Associated with CVD Risk Reduction in Transplant Recipients

The most common cause of morbidity and mortality in patients with chronic kidney disease (CKD) is cardiovascular disease (CVD). The optimal therapy for patients with kidney failure is kidney transplantation; there were more than 16,000 kidney transplantations performed in the United States in 2013. CVD is the leading cause of death among individuals living with a functioning transplant. Recommendations from ... Read More »