Pain and Decline in Kidney Function and Risk of Mortality

Chronic nonmalignant pain affects nearly 100 million people in the United States, accounting for 20% of outpatient visits, 12% of all prescriptions, and >$100 billion per year of direct and indirect costs. Chronic pain is more common in individuals with comorbid conditions such as cardiovascular disease, diabetes mellitus, and hypertension. Chronic kidney disease (CKD) is a frequent consequence of those ... Read More »

No Change in Prevalence of Diabetic Kidney Disease Since 1988

There have been increases in the prevalence of both diabetes mellitus and diabetic kidney disease (DKD) over the past 20 years. Worldwide, the most common cause of kidney disease is diabetes, leading to complications that include end-stage renal disease, cardiovascular disease, infection, and death. The clinical manifestations of chronic kidney disease in the setting of diabetes or DKD are albuminuria, ... Read More »

November/December 2016: News Briefs

CMS Announces Dialysis Facility Compare Five-Star Ratings System Results Satellite Healthcare Recognized by CMS Five-Star Ratings System Satellite Healthcare has been identified by the Centers for Medicare & Medicaid Services (CMS) Five-Star Quality Rating System as having the highest percentage of top-rated dialysis centers of the ten largest national dialysis providers. In a press release from Satellite, Brigitte Schiller, MD, ... Read More »

October 2016: News Briefs

Analysis of Secondary Data on Patiromer Results of a pre-specified exploratory analysis of data from the phase 3 OPAL-HK trial of Veltassa® (patiromer) for oral suspension were reported online in Kidney International. Results of the newly published analysis demonstrated that patients taking patiromer had significant decreases in systolic and diastolic blood pressure and reduced levels of aldosterone in the blood. ... Read More »

Aspirin Use Not Associated with CVD Risk Reduction in Transplant Recipients

The most common cause of morbidity and mortality in patients with chronic kidney disease (CKD) is cardiovascular disease (CVD). The optimal therapy for patients with kidney failure is kidney transplantation; there were more than 16,000 kidney transplantations performed in the United States in 2013. CVD is the leading cause of death among individuals living with a functioning transplant. Recommendations from ... Read More »

Report: Ultrafiltration Rate Thresholds in Maintenance Hemodialysis

The Dialysis Outcomes Quality Initiative (DOQI) was launched in 1995 by the National Kidney Foundation (NFK) with the aim of improving outcomes for patients with end-stage renal disease (ESRD) receiving maintenance dialysis. The initiative resulted in the publication of clinical practice guidelines in 1997 that addressed dialysis treatment adequacy. Since 1997, there have been two updates to the guidelines; however, ... Read More »

Acute Kidney Injury after Major Surgery Common

Acute kidney injury is a common postoperative complication; approximately one third of cases of AKI acquired in the hospital setting occur postoperatively. Observational evidence shows an association of AKI with adverse outcomes, including progression to chronic kidney disease and end-stage renal disease (ESRD), and death. There are few preventive or therapeutic interventions that are effective in AKI; strategies and therapeutics ... Read More »

Advance Care Planning Model Facilitated by Nephrologists

Patients with end-stage renal disease (ESRD) requiring renal replacement therapy (RRT) have approximately one-third the life expectancy as that of the general population: a patient 67 years of age with ESRD has a life expectancy of 4.6 years compared with 15.5 years in the general population. The fastest growing sector of the population on dialysis is among patients more than ... Read More »

October 2016: Abstract Roundup

Acute Kidney INjury Results from the Acute Renal Failure Trial Network Study Clinical Journal of the American Society of Nephrology. 2016;11(8):1335-1342 In trials of more intensive versus less intensive renal replacement therapy (RRT), there have been adverse effects associated with more intensive RRT that account for the absence of observed benefit. Finnian R. Mc Causland, MD, and colleagues recently conducted ... Read More »

September 2016: News Briefs

KDIGO Launches New Guidelines App Kidney Disease: Improving Global Outcomes (KDIGO) has announced the launch of a redesigned app for both iOS and Android devices. The app, KDIGO Mobile, offers a modern user interface and intuitive user experience, according to a press release from KDIGO. Users also have unlimited access to the KDIGO library of clinical practice guidelines for nephrology. ... Read More »