Consumption of Fruits and Vegetables Decrease Risk of Cardiovascular Mortality

San Diego—An international group of researchers, led by Camilo G. Sotomayor, conducted a prospective cohort study to examine the associations of consumption of fruits and vegetables following kidney transplantation and the risk of cardiovascular mortality. The study population included an extensively phenotyped cohort of renal transplant recipients with long-term follow-up. Results of the study were reported during a poster session ... Read More »

Neurocognitive Impairment in CKD in Children and Young Adults May Be Functional Rather than Structural

Children and adults with chronic kidney disease (CKD) often experience neurocognitive dysfunction. Children with CKD may have reduced performance in attention, memory, executive function, verbal and nonverbal reasoning, and spatial processing. Global cognitive performance may be reduced in adults with CKD; further, patients may experience specific cognitive impairments such as attention, memory and executive functioning, and dementia. There is relatively ... Read More »

Metabolic Abnormality and Obesity Associated with Rate of CKD Progression

Obesity, a worldwide major health problem, is associated with increased risk for type 2 diabetes mellitus, cardiovascular disease, cerebrovascular events, and malignancy, resulting in increased rates of cardiovascular and all-cause mortality. Studies have also demonstrated an increased risk of developing incident chronic kidney disease (CKD); however, it is unclear whether obesity itself worsens kidney function in patients with CKD. Results ... Read More »

Reduced eGFR Associated with Increased Sedentary Time in Canadian Study

In the general population, ≥50% of awake time is spent in sedentary activities. Studies have shown that sedentary behavior, independent of physical activity level, is a risk factor for adverse health outcomes, including increased risk for diabetes and all-cause and cardiovascular mortality, and higher rates for chronic disease. There is an association between increased sedentary time and lower health-related quality ... Read More »

Bundled Payment Reform Effects Rates of Vitamin D Therapy Initiation

Beginning in 1972, all patients in the United States with end-stage renal disease (ESRD) have been eligible for Medicare. The number of patients with ESRD requiring maintenance hemodialysis has increased from 16,000 to >400,000 in the years since. Individuals in that patient population represent <1% of all Medicare beneficiaries, but costs for those on maintenance hemodialysis account for 7.4% of ... Read More »

Concentration of Serum Calcitriol Associated with Kidney Function Decline in Older Adults

Incident heart failure and decline in kidney function are often linked conditions; both are prevalent in older individuals and are associated with high morbidity and mortality. Previous studies have demonstrated an association between lower concentrations of 25-hydroxyvitamin D and progression of chronic kidney disease (CKD), heart failure, and mortality; diabetes, higher blood pressure, and inflammation are also key risk factors ... Read More »

Hypoglycemic-Related Hospitalizations Associated with Increased Post-ESRD Mortality

Thirty to 40% of patients with diabetes mellitus will develop chronic kidney disease (CKD), and 44% of cases of incident end-stage renal disease (ESRD) in the United States are associated with diabetic kidney disease. The annual mortality rate of diabetic patients with ESRD is greater than among those with other causes of ESRD, creating a need to identify modifiable risk ... Read More »

Lanreotide and Decline in Kidney Function in Patients with ADPKD

A 2017 review of epidemiology literature resulted in an estimated prevalence of autosomal dominant polycystic kidney disease (ADPKD) of approximately three to four per 10,000. Patients with ADPKD experience progressive cyst formation in both kidneys and loss of renal function. In the majority of affected patients, end-stage renal disease requiring renal replacement therapy (RRT), dialysis or kidney transplantation, occurs between ... Read More »

Supplementation with Omega-3 Polyunsaturated Fatty Acids to Prevent Vascular Access Failure

Worldwide, the most common renal replacement therapy is hemodialysis, best performed using a functioning arteriovenous vascular access; aestablishing and maintaining functional arteriovenous vascular access remains a major challenge associated with dialysis care. Dysfunction of arteriovenous fistula (AVF) and graft (AVG) leads to prolonged use of central venous catheters and is associated with repeat hospitalization and procedures as well as higher ... Read More »

Patient Perspectives on Chronic Kidney Disease Monitoring and Self-Management

Self-management is required of patients with chronic diseases to limit disease progression, including regular monitoring visits for provider assessment, feedback, and adjustments to the care plan. These self-management directives involve a shift from passive to active disease management for the patient and require shifts in provider to patient communication approaches. Enabling higher levels of patient engagement can be informed by ... Read More »