Kidney Week 2014

Proton Pump Inhibitors versus H2 Blockers and Risk of Hypomagnesemia

Philadelphia—At many transplant centers, the use of proton pump inhibitors (PPIs) has replaced the use of H2 receptor blockers (H2B) for gastrointestinal prophylaxis, despite a lack of evidence for superior efficacy of PPIs over H2Bs. According to researchers, although PPIs are generally safe medications, their use has been associated with hypomagnesemia due to impaired gastrointestinal absorption. Mohamad Alhosaini, MD, and ... Read More »

Induction with Alemtuzumab Has Low Incidence of BK Nephropathy

Philadelphia—Kidney injury and graft failure are increasingly being associated with BK nephropathy. Current literature suggests an association between high immunosuppression dose and increased incidence of BK viruria, viremia, and nephropathy. According to Pradeep Vaitla, MD, and colleagues, most transplant centers in the United States use antibody induction with rabbit antihymocyte globulin or alemtuzumab to minimize maintenance immunosuppression. The researchers recently ... Read More »

Anemia Risk Factor for AKI in Hospitalized Patients

Philadelphia—Anemia increases the risk of acute kidney injury (AKI) in hospitalized patients and the risk may be modified with correction of the anemia. Those were among the findings of research presented in a poster session during Kidney Week 2014 by Melanie Godin, MD, and colleagues. The poster was titled Anemia Is a Risk Factor for Development of Acute Kidney Injury ... Read More »

PGNMID and Progression of Renal Disease

Philadelphia—Even with treatment, proliferative glomerulonephritis associated with non-organized monoclonal Immunoglobulin (Ig) deposits (PGNMID) has poor renal outcomes, according to Gauri Bhutani, MD, and colleagues. That was one of the findings of a study conducted by Dr. Bhutani et al. during a poster session at Kidney Week 2014. The poster was titled Progression of Renal Disease and Treatment Outcomes in Proliferative ... Read More »

Renal Function Outcomes with Envarsus® versus Prograf®

Philadelphia—In the first year following kidney transplantation, two formulations of tacrolimus are associated with good renal function, according to results of a study conducted by Lionel Rostaing, MD, PhD, and colleagues. Study results were reported during a poster session at Kidney Week 2014 in a poster titled Renal Function Outcomes Associated with Once-Daily MeltDose® Tacrolimus versus Twice-Daily Tacrolimus, a Phase ... Read More »

Cardiac History and Dialysis Duration Associated with Elevated Risk of EAMI

Philadelphia—Kidney transplant recipients with a history of cardiovascular disease and longer duration of dialysis were at increased risk of early post-operative acute myocardial infarction (EAMI) in a study conducted recently by Maya Deeb and colleagues. The researchers reported study results during a poster session at Kidney Week 2014 in a poster titled Early Post-Operative Acute Myocardial Infarction in Kidney Transplant ... Read More »

HLA-DP Mismatch and Graft Outcomes

HLA-DP Mismatch and Graft Outcomes Philadelphia—The majority of human leukocyte antigen (HLA)-A, -B, -DR zero HLA mismatch transplants are mismatched for HLA-DP, according to results of a study conducted by Nissreen S. Elfadawy, MD, and colleagues. The researchers presented study results during a poster session at Kidney Week 2014 in a poster titled HLA-DP Mismatch among the Zero GLA-A, -B, ... Read More »

Outcomes of ABO Compatible and Incompatible Kidney Transplantation

Philadelphia—Researchers in Korea recently conducted a study to compare outcomes in spousal donor kidney transplantations with ABO incompatible kidney transplantations versus ABO compatible kidney transplantations. Ji Hyun, MD, and colleagues reported results of the study during a poster session at Kidney Week in a poster titled Comparison of Outcomes from Spousal Donor Graft Between ABO Compatible and Incompatible Kidney Transplantation. ... Read More »

Outcomes in Sensitized Pregnant Kidney Transplant Recipients

Philadelphia—An increased risk of antibody mediated rejection (AMR), graft loss, and adverse pregnancy outcomes was seen in sensitized kidney transplant recipients in a single-center retrospective cohort study. The study was conducted by Maria Ajaimy, MD, and colleagues and reported during a poster session at Kidney Week 2014. The poster was titled Increased Risk of Antibody Mediated Rejection and Graft Loss ... Read More »

Educating Dialysis Patients about Emergency Preparedness

Philadelphia—A multidisciplinary approach in an outpatient dialysis center to emergency preparedness in dialysis patients is feasible and effective to educate patients about creating plans for maintaining dialysis during disasters. That was the main finding of a study conducted recently by Anuradha Wadhwa, MD, and colleagues. The researchers presented study results in a poster session during Kidney Week 2014 in a ... Read More »