Focus on Transplantation

Combined Liver-Kidney Transplantation in Children with ARPKD

The most common cystic kidney disease in the pediatric population is autosomal recessive polycystic kidney disease (ARPKD); it occurs in one of 20,000 live births, and is associated with mutations in one gene, polycystic kidney and hepatic disease 1 (PKHD1), on chromosome 6p12. ARPKD is a significant cause of kidney- and liver-related morbidity and mortality in children. The mortality rate ... Read More »