Focus on Transplantation

Nonwhite Organ Transplant Recipients at High Risk for Skin Cancer

In 2015, approximately 13,000 nonwhite (black, Asian, Hispanic, Pacific Islander) individuals received an organ transplant; this population has a higher incidence of new skin cancers compared with comparable nontransplant recipients. This risk increases over time with continued exposure to immunosuppression regimens. Squamous cell carcinoma (SCC) is increased 65-fold, basal cell carcinoma (BCC) is increased 10-fold, and melanoma is increased 3-fold ... Read More »

Combined Liver-Kidney Transplantation in Children with ARPKD

The most common cystic kidney disease in the pediatric population is autosomal recessive polycystic kidney disease (ARPKD); it occurs in one of 20,000 live births, and is associated with mutations in one gene, polycystic kidney and hepatic disease 1 (PKHD1), on chromosome 6p12. ARPKD is a significant cause of kidney- and liver-related morbidity and mortality in children. The mortality rate ... Read More »