Cover Stories

Brain Atrophy Faster in PD Patients than in Non-Dialysis Dependent CKD Patients

There was a significantly greater decline in normalized gray matter volume (GMV) in patients receiving peritoneal dialysis (PD) compared with patients with non–dialysis-dependent chronic kidney disease (NDD-CKD), according to results of a study conducted recently by Kazuhiko Tsuruya, MD, PhD, and colleagues at the Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan. The researchers reported results of the cross-sectional ... Read More »

Hemodialysis Frequency and Preservation of RKF

Twice-weekly hemodialysis for the first 6 months or longer following initiation of dialysis helped protect residual kidney function (RKF). That was one of the findings of a cohort study conducted recently by Minmin Zhang, MD, and colleagues and reported in the American Journal of Nephrology [2-14;40:140-150]. According to the researchers, RKF is increasingly being seen as an important factor influencing ... Read More »

Care for Dialysis-Dependent Patients Following Hurricane Sandy

 “So many people take emergency preparedness for granted until an emergency strikes.  This study shows that with good planning, and the help of the KCER (Kidney Community Emergency Response) coalition, providers, dialysis facilities and patients alike were able to achieve early dialysis for many patients, likely averting emergency department visits and hospitalizations—and even death.  This practice, along with other protective ... Read More »

Use and Costs of Medications to Manage CKD-MBD in Medicare Beneficiaries

“Our research highlighted the fact that Part D net costs for CKD-MBD medications increased at a faster rate than costs for all Part D medications in dialysis patients, despite relatively stable use of these medications. This suggested that, on average, acquisition prices of CKD-MBD medications were increasing faster than other drug categories. In addition, the odds of using branded more ... Read More »

CKD in Older Adults and Medication Safety

“Chronic kidney disease is common among older adults prescribed metformin for type 2 diabetes. Prescribers need to consider this when treating older adults with diabetes.” —Deborah Huang, MD, MPH Chronic kidney disease (CKD) is a common comorbidity in older adults prescribed metformin for treatment of type 2 diabetes mellitus. In a study population of older adults prescribed metformin for diabetes, ... Read More »

Managing Elderly Patients with DM and CKD

Elderly patients with chronic kidney disease (CKD) and diabetes mellitus (DM) present challenges in the management of their conditions, including specific characteristics that affect metabolic control and therapeutic measures. Pedro Iglesias, MD, Manuel Heras, MD, and Juan J. Diez, MD, provided a review of some of these management issues in Revista Nefrología [2014;34(3):285-292]. The prevalence of DM increases with age ... Read More »

Timely Education May Inform Patients’ Perspectives on Vascular Access

“Vascular access is a surgical intervention that has serious physical and psychosocial consequences for patients requiring hemodialysis. Some patients believe that vascular access is disfiguring, threatening, and signifies a medical mechanization and intrusion of their own body. To provide patient-centered hemodialysis care, we need to address patients’ fears and concerns about the creation and management of vascular access.” -Allison Tong, ... Read More »

RRT Delivery in Patient with Ebola Virus Disease

“Ebola virus disease in resource-rich settings can range from mild disease to severe life threatening illness with organ failures. However, with aggressive supportive care and life support measures available in resource-rich settings (volume resuscitation, hemodialysis, and mechanical ventilation), death from Ebola virus disease should be much less common than in resource-poor settings. In our opinion, this report confirms that with ... Read More »

Predictors of Progression to Chronic Dialysis among Survivors of AKI Identified

Pre-existing kidney disease, hypertension, and global comorbidity are all predictors of the need for chronic dialysis among survivors of acute kidney injury (AKI) requiring dialysis who initially become dialysis independent. That was the primary finding of a study conducted recently by Ziv Harel, MD, and colleagues. Study results were reported in BMC Nephrology [doi:10.1186/1471-2369-15-1214]. AKI is a common complication of ... Read More »

Consensus Conference Offers Report on Diabetic Kidney Disease

The increase in type 2 diabetes worldwide has led to an increase in the incidence and prevalence of diabetes mellitus, which has in turn had a significant impact on the development of diabetic kidney disease (DKD). Further, diabetes and kidney disease are common chronic conditions; people with diabetes may have other etiologies of chronic kidney disease (CKD) in addition to ... Read More »