Conference Coverage

Pathways and Biomarkers for Progression of Diabetic Kidney Disease

New Orleans—The leading cause of end-stage renal disease (ESRD) is diabetic kidney disease. According to researchers, understanding of molecular pathways involved in the initiation and progression of diabetic kidney disease facilitates development of biomarkers and identification of drug targets. Skander Mulder, MD, and colleagues conducted a study designed to identify molecular pathways associated with progressive loss of kidney function in ... Read More »

Size Mismatch in Pediatric Living Donor Kidney Transplantation

New Orleans—Previous studies have demonstrated an association between small donor body size in relation to recipient body size and increased risk of graft loss following kidney transplantation. There are few data, however, on this relationship in young children undergoing living donor kidney transplantation, a patient population with a greater possibility of size mismatch. Heather L. Wasik, MD, and colleagues at ... Read More »

Options Education Impacts Modality Choice for ESRD Patients

New Orleans—Patients with chronic kidney disease making decisions regarding options for renal replacement therapy (RRT) may be helped with the use of education programs on dialysis; however, there are few data on the impact of educational programs on modality choice. Yue Jiao, MD, and colleagues at Fresenius Medical Care North America (Waltham, MA) conducted an analysis designed to examine the ... Read More »

Tolvaptan Improved Hyponatremia in Patient with Melanoma

New Orleans—The 10-year survival rate for patients with metastatic melanoma is <10%. The majority of patients are treated with systemic therapy, and there are associations between immunotherapeutic agents and durable response in some patients. In 1998, the FDA approved high dose interleukin-2 (IL-2) for treatment of metastatic melanoma. Common adverse effects include fever, chills, hypotension, cardiac arrhythmias, oliguria, volume overload, ... Read More »

Rapid Correction of Severe Hyponatremia

New Orleans—In patients with severe hyponatremia, rapid correction of serum sodium can result in serious adverse clinical consequences, including central pontine myelinolysis (CPM). There are few available data on the clinical risk factors associated with rapid correction of hyponatremia and on the incidence of CPM among patients with severe hyponatremia. Jason C. George, MD, and colleagues utilized data on 1352 ... Read More »

Kidney Injuries at a Level 1 Trauma Center

Orlando—Elmhurst Hospital Center at the Icahn School of Medicine in Queens, New York, is a level 1 trauma center. Approximately 3% of all trauma admissions at the center are renal trauma cases; among patients who sustain abdominal trauma, as many as 10% of trauma admissions involve renal trauma. Researchers at the center, led by Jayaramakrishna Depa, MD, conducted a retrospective ... Read More »

Education Program Helps Patients Make Modality Decisions

Orlando—In the United States, end-stage renal disease (ESRD) represents a burden to public health and increases pressure on healthcare costs. Data from 2014 identified approximately 680,000 prevalent cases of ESRD in the United States; up to 38% of incident patients did not receive care from a nephrologist prior to renal replacement therapy initiation. Percentages of treatment modalities in the United ... Read More »

Facilitating Transition of Care from Hospital Discharge to Outpatient Dialysis Unit

Orlando—The transition from hospital discharge to return to the dialysis unit is a vulnerable time for patients on maintenance hemodialysis. Unsafe transitions put patients at risk for adverse outcomes, visits to the emergency department (ED), and hospital readmission. At the University of Pennsylvania Hospital, 44% of dialysis patients discharged from the hospital had at least one ED visit within 30 ... Read More »

Care Coordination Program Improved Outcomes and Reduced Costs

Orlando—Chronic kidney disease (CKD) exacts a burden on healthcare resources and is a serious public health concern. Beverly Everett, MD, and colleagues at Cigna Health and Life Insurance Company recently designed a study to assess the impact on outcomes of utilization of a pilot program designed to identify and engage CKD patients who are at risk for progression from CKD ... Read More »

Uncontrolled Gout among Patients with Chronic Kidney Disease

Orlando–Gout, caused by primarily by elevated serum uric acid in the blood, is the most common form of inflammatory arthritis. Recommendations in guidelines from the American College of Rheumatology call for lowering serum uric acid levels to <6 mg/dL for all patients with gout. Elevated serum uric acid is also associated with chronic kidney disease and results of previous studies ... Read More »