Conference Coverage

Fluid Overload in Patients with AKI Requiring CRRT and Major Adverse Events

San Diego—In critically ill patients with acute kidney injury (AKI), there is an association between fluid overload and adverse outcomes. Connor W. Woodward, and colleagues recently conducted a study designed to examine the association between fluid overload and major adverse kidney events in patients with CKI requiring continuous renal replacement therapy (CRRT). Results of the single-center retrospective study were reported ... Read More »

Emergency Department Prediction Model for Acute Kidney Injury

San Diego—More than 50% of community-acquired acute kidney injury (AKI), an independent risk factor for mortality, are identified in the emergency department (ED). The ED is the primary route for acute hospital admissions. The facilitation of prompt medical assessment and treatment depends on accurate stratification of risk. David A. Foxwell, MD, and colleagues in Wales, United Kingdom, recently conducted a ... Read More »

Cost-Effectiveness of Patiromer for Hyperkalemia in CKD Patients Using RAASIs

Orlando—Renin-angiotensin-aldosterone system inhibitors (RAASIs) are of benefit to patients with chronic kidney disease (CKD); however, providers may avoid or discontinue use of RAAIs due to concerns related to RAASI-induced hyperkalemia. Patiromer is a non-absorbed potassium-binding polymer for the treatment of hyperkalemia, including patients on RAASIs. Mark Bounthavong, PharmD, MPH, and colleagues recently conducted a study to assess the cost-effectiveness of ... Read More »

Real-World Utilization of Patiromer among Medicare Advantage Patients

Orlando—The real-world utilization of patiromer, a sodium-free, potassium-binding polymer, in the treatment of hyperkalemia was the subject of a study conducted recently by Robert Toto, MD, and colleagues. The study included patients with hyperkalemia who had Medicare Advantage insurance. Study results were reported during a poster session at AMCP NEXUS 2018 in a poster titled Real-World Utilization of Hyperkalemia Management ... Read More »

Proteinuria Is a Marker of Uncontrolled Hypertension

Austin, Texas—Proteinuria is a marker for cardiovascular disease. Identification of patients with proteinuria allows for early treatment to decrease the cardiovascular risk. Michael P. Carson, MD, and colleagues conducted a retrospective chart review designed to identify hospitalized patients with proteinuria, examine the prevalence of concurrent use of medications known to decrease the level of proteinuria, and determine the number of ... Read More »

Incidence and Timing of ESRD from ADPKD Varies by Race

Austin—All races and ethnicities are affected by autosomal dominant polycystic kidney disease (ADPKD). However, despite an expectation that the prevalence of ADPKD would be similar among races, assessments in published literature regarding the incidence and age of end-stage renal disease (ESRD) secondary to ADPKD conflict among black and white patient populations with ADPKD. Erin L. Murphy, MD, and colleagues conducted ... Read More »

Sleep Apnea Severity and Mortality in CKD and ESRD Patients

Austin, Texas—The association between sleep apnea and mortality is well established in the general population; there are few data on this association in patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD). Hossam Abdalla, MD, and colleagues conducted a study designed to examine the association between the severity of sleep apnea and mortality in patients with advanced CKD ... Read More »

Cardiac Output and Net Volume Balance in ICU Patients

Austin—Volume management for patients in the intensive care unit (ICU) aims to optimize intravascular volume and maximize cardiac output. Following giving volume to volume-depleted patients, cardiac output tends to increase. In volume-overloaded patients with end-stage renal disease, cardiac volume tends to increase with ultrafiltration, and to decrease with ultrafiltration in patients with ESRD who are prone to intradialytic hypotension. In ... Read More »

Fenofibrate Use Associated with Lower Rates of CKD Incidence and Progression

Austin—In patients with type 2 diabetes, abnormalities in lipid metabolism may contribute to the development and progression of chronic kidney disease (CKD). Results from the ACCORD (Action to Control Cardiovascular Risk in Diabetes) trial  demonstrated that fenofibrate induced early and reversible reduction in kidney function. Rebecca Frazier, MD, and colleagues conducted a post-hoc analysis of data from the ACCORD trial ... Read More »

Older Kidney Transplant Recipients More Adherent to Medications

Austin—There are few available data regarding health and its relationship to adherence to medications as it relates to age in recipients of kidney transplants. Marc Emos, MD, and colleagues at SUNY Downstate Medical Center, Brooklyn, New York, conducted face-to-face interviews with 16 long-term patients chosen at random from the outpatient transplant clinic at the center. A two-question survey was used ... Read More »