Conference Coverage

New-Onset Diabetes after Kidney Transplantation in ADPKD Patients

Boston—New-onset diabetes after transplantation (NODAT) is a common complication and it an independent factor associated with mortality and renal allograft failure. There are other risk factors for developing NODAT, including obesity, hepatitis C virus, cytomegalovirus infection, and use of corticosteroids or calcineurin inhibitors (CNIs). Other factors are the type of CNI used, ethnicity (African, South Asian), and impaired fasting glucose. ... Read More »

AKI Classification with Proposed Criteria Correlates with Recovery after Partial Nephrectomy

Washington, DC—Following partial nephrectomy, parenchymal mass reduction and ischemia are the primary causes of an acute increase in serum creatinine. During a poster session at the 16th Annual Meeting of the Society of Urologic Oncology, Zhiling Zhang, MD, and colleagues presented results of a study designed to evaluate etiologies of AKI after partial nephrectomy and the predictive significance of those ... Read More »

Vascular Calcification in Kidney Transplant Patients

San Diego—Researchers in Italy recently conducted a study designed to assess (1) the prevalence of bone mineral anomalies, (2) the factors related to femoral bone mineral density, and (3) the relationship of femoral bone mineral density with aortic calcifications and coronary calcifications in a cohort of kidney transplantation patients who underwent femoral DEXA (dual-energy x-ray absorptiometry). To avoid confounders between ... Read More »

Oral versus Injectable Vitamin D Receptor Activator in Hemodialysis Patients

San Diego—In hemodialysis patients with infection, vitamin D receptor activator (VDRA) had been reported to be associated with improved survival. However, according to researchers, the optimal route of administration of VDRA to prevent death from the infection is unclear. Shigeru Tanaka, MD, and colleagues recently conducted a study designed to examine the comparative effectiveness of VDRA between oral administration and ... Read More »

Changes in EKGs of Hyperkalemia on Hemodialysis Patients

San Diego—According to researchers, the available data on the effects of hyperkalemia on the electrocardiogram (EKG) of patients on chronic hemodialysis are inconsistent. Muzzaffar Hussain, MD, and colleagues examined EKGs of 128 chronic hemodialysis patients with clotted grafts or fistulas. They reported results of the analysis during a poster session at the American Society of Nephrology Kidney Week 2015 in ... Read More »

Home Hemodialysis and Peritoneal Dialysis Growth Before and After 2011

Seattle—During the past decade, use of both home hemodialysis and peritoneal dialysis has increased in the United States. However, according to Eric Weinhandl, MS, PhD, and Alan Collins, MD, of the University of Minnesota, Minneapolis, there are few data on the temporal and geographic variations in the rates of growth. It is possible that access barriers may be associated with ... Read More »

Peritoneal Dialysis Technique Failure Incidence Declines

Seattle—There has been a gradual decline in the incidence of peritoneal dialysis failure since 2005; however, there has also been an increase in the number of patients initiating peritoneal dialysis. Technique failure, a common complication of peritoneal dialysis, is clinically disruptive because patients transitioning to hemodialysis may need aggressive ultrafiltration for fluid overload, antibiotic treatment for peritonitis, or placement of ... Read More »

Belatacept-Based Immunosuppression Produces Long-Term Benefits

Short-term outcomes of kidney transplantation have been improved with the use of prolonger maintenance immunosuppressive therapy; however, there are few data on the long-term effect on allograft survival. Belatacept is a selective costimulation blocker developed to improve long-term outcomes in kidney transplant recipients by providing immunosuppression less the toxic effects of calcineurin inhibitors. Current standard-of-care immunosuppressive regimens combine calcineurin inhibitors ... Read More »

Mental Health History Not Associated with Transplant Outcomes

San Diego—There was no association between a history of mental illness and poor outcomes following kidney transplantation in a study conducted recently in Canada. Istvan Mucsi, MD, PhD, and colleagues reported results of the single-center, retrospective cohort study during a poster session at Kidney Week 2015 in a poster titled Pre-Transplant Mental Health Disorders and Non-Adherence and Post-Transplant outcomes in ... Read More »

Hyponatremia and Risk of Mortality in Hemodialysis Patients

San Diego—In the general population, due in part to underlying diseases including congestive heart failure and cirrhosis associated with low serum sodium concentrations, hyponatremia is associated with an increased risk of mortality. There have been studies reporting that hyponatremia itself further increases the risk of death. According to researchers led by Yukako Ohyama, MD, there are few data on the ... Read More »