Conference Coverage

Uncontrolled Gout among Patients with Chronic Kidney Disease

Orlando–Gout, caused by primarily by elevated serum uric acid in the blood, is the most common form of inflammatory arthritis. Recommendations in guidelines from the American College of Rheumatology call for lowering serum uric acid levels to <6 mg/dL for all patients with gout. Elevated serum uric acid is also associated with chronic kidney disease and results of previous studies ... Read More »

Specialized Disease Management Program Reduced Costs and Inpatient Admissions

Orlando—Optum’s Disease Management (DM) program utilizes communication via telephone and hard copy between renal specialty nurses and patients and healthcare providers to enhance patients’ knowledge of chronic kidney disease (CKD) and ways to maximize their healthcare. Employers purchase the DM program to enable patient-access. In 2016, a meta-analysis of the efficacy of DM programs focused on CKD demonstrated improved quality ... Read More »

Obinutuzumab Safe and Effective for B-Cell Depletion in Transplant Candidates

Chicago—In allosensitized patients with end-stage renal disease (ESRD), the efficacy of rituximab for desensitizing and enabling kidney transplantation is limited; tissue B-cell depletion is incomplete. Robert R. Redfield III, MD, and colleagues recently conducted an open-label phase 1b study to test the hypothesis that obinutuzumab may be more effective for desensitization than rituximab. Obinutuzumab is a glycoengineered type 2 anti-CD20 ... Read More »

Etelcalcetide Safe and Efficacious over 18 Months

Orlando—Researchers led by Sunfa Cheng, MD, recently conducted an analysis of data from a 52-week open label extension trial and an open label extension trial of up to 2.5 years of etelcalcetide, an intravenous calcimimetic that reduced secondary hyperparathyroidism in hemodialysis patients. The efficacy of etelcalcetide in reducing parathyroid hormone was demonstrated in three phase 3 trials. The researchers reported ... Read More »

Glycemic Control Levels and Infections in Hemodialysis Patients with Diabetes Mellitus

Chicago—There are few data on the associations between glycemic control and infections requiring hospitalization or fatal infections in hemodialysis patients with diabetes mellitus. Using data from the US Renal Data System and from electronic health records from a large dialysis provider in the United States, Jinnie J. Rhee, MD, and colleagues recently conducted a study to examine such associations. They ... Read More »

App Aids in Patient Training for Self-Care In Center or At Home

Chicago—It is important to provide education for dialysis patients regarding their therapy options, and maintenance of kidney function and health. Previous studies have demonstrated that educated patients make better choices and are more adherent to their therapy. However, training is labor intensive and requires hours of staff time; those constraints have been cited as a barrier to patients in selecting ... Read More »

Pretransplant Duration of Dialysis Risk Factor for Post-Transplant Mortality

Chicago—There are few data available on the effects of pre-transplant dialysis modality or duration of pre-transplant dialysis on clinical outcomes following kidney transplantation. Researchers in Korea, led by Hyunjeong Cho, MD, recently conducted an analysis of data from the Korean Health Insurance Review & Assessment Service. The data were compiled from records of 35,422 adults who initiated hemodialysis and peritoneal ... Read More »

Dietary Counseling Improves Compliance with CKD Dietary Restrictions

Chicago—In patients with chronic kidney disease (CKD), a key element of multidisciplinary care is dietary restriction. However, according to researchers, there are few data on barriers to adherence to dietary regimens important in CKD care. Maya K. Rao, MD, and colleagues recently conducted a cross-sectional study among English and Spanish speaking patients with stage 4 and 5 CKD. The researchers ... Read More »

Risk of ESRD in AKI Patients Requiring Temporary Dialysis

Boston—Researchers at Case Western Reserve University recently conducted a study examining the progression of acute kidney injury (AKI) to end-stage renal disease (ESRD) among patients with AKI who require temporary dialysis. Previous studies have reported data on the progression of severe AKI with dialysis to ESRD among patients with chronic kidney disease (CKD), and among patients in certain subgroups such ... Read More »