National Kidney Foundation Spring 2018 Clinical Meetings

National Kidney Foundation Spring 2018 Clinical Meetings

Hospital Readmissions among Peritoneal Dialysis Patients

Austin—Patients receiving in-center dialysis commonly require hospital readmission; however, there are few data on readmissions among patients undergoing peritoneal dialysis. Abyalew Sahlie, MD, and colleagues utilized national administrative data to examine the burden and correlates of hospital readmission among patients in the United States undergoing peritoneal dialysis. Results of the analysis were reported during a poster session at the NKF ... Read More »

Proteinuria Is a Marker of Uncontrolled Hypertension

Austin, Texas—Proteinuria is a marker for cardiovascular disease. Identification of patients with proteinuria allows for early treatment to decrease the cardiovascular risk. Michael P. Carson, MD, and colleagues conducted a retrospective chart review designed to identify hospitalized patients with proteinuria, examine the prevalence of concurrent use of medications known to decrease the level of proteinuria, and determine the number of ... Read More »

Incidence and Timing of ESRD from ADPKD Varies by Race

Austin—All races and ethnicities are affected by autosomal dominant polycystic kidney disease (ADPKD). However, despite an expectation that the prevalence of ADPKD would be similar among races, assessments in published literature regarding the incidence and age of end-stage renal disease (ESRD) secondary to ADPKD conflict among black and white patient populations with ADPKD. Erin L. Murphy, MD, and colleagues conducted ... Read More »

Cardiac Output and Net Volume Balance in ICU Patients

Austin—Volume management for patients in the intensive care unit (ICU) aims to optimize intravascular volume and maximize cardiac output. Following giving volume to volume-depleted patients, cardiac output tends to increase. In volume-overloaded patients with end-stage renal disease, cardiac volume tends to increase with ultrafiltration, and to decrease with ultrafiltration in patients with ESRD who are prone to intradialytic hypotension. In ... Read More »

Sleep Apnea Severity and Mortality in CKD and ESRD Patients

Austin, Texas—The association between sleep apnea and mortality is well established in the general population; there are few data on this association in patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD). Hossam Abdalla, MD, and colleagues conducted a study designed to examine the association between the severity of sleep apnea and mortality in patients with advanced CKD ... Read More »

Fenofibrate Use Associated with Lower Rates of CKD Incidence and Progression

Austin—In patients with type 2 diabetes, abnormalities in lipid metabolism may contribute to the development and progression of chronic kidney disease (CKD). Results from the ACCORD (Action to Control Cardiovascular Risk in Diabetes) trial  demonstrated that fenofibrate induced early and reversible reduction in kidney function. Rebecca Frazier, MD, and colleagues conducted a post-hoc analysis of data from the ACCORD trial ... Read More »

Older Kidney Transplant Recipients More Adherent to Medications

Austin—There are few available data regarding health and its relationship to adherence to medications as it relates to age in recipients of kidney transplants. Marc Emos, MD, and colleagues at SUNY Downstate Medical Center, Brooklyn, New York, conducted face-to-face interviews with 16 long-term patients chosen at random from the outpatient transplant clinic at the center. A two-question survey was used ... Read More »

ADPKD and Subclinical Metabolic Abnormalities

Austin—Patients with autosomal dominant polycystic kidney disease (ADPKD) experience high lifetime morbidity, related to both renal sequelae and to cardiovascular risk. Recent studies have identified abnormal regulation of pathways affecting cellular signaling, proliferation, and apoptosis in patients with ADPKD. Future targets for treatment may include modifying factors related to abnormal lipid metabolism, insulin insensitivity, early hypertension, as well as other ... Read More »

Female Sex Protective Mortality Related to AKI

Austin—Patients who experience acute kidney injury (AKI) are at increased risk for short- and long-term mortality. Results of previous studies have revealed a higher risk of mortality among males with AKI; female sex has been shown to be protective in both the development of AKI and the AKI-related mortality risk. The majority of those studies utilize univariate analyses, without consideration ... Read More »

Patients May Only Partially Report Symptom Burden of Hemodialysis

Austin, Texas—Patients on maintenance dialysis experience substantial burden of symptoms that are associated with impaired quality of life. Symptom control is cited as a top research priority by patients, but results of previous studies suggest that providers may underestimate the burden on patients. Researchers at the University of North Carolina, Chapel Hill, led by Adeline Dorough, BS, conducted a qualitative ... Read More »