Kidney Week 2019

Nutritional Predictors of All-Cause Mortality in Hemodialysis Patients

Washington, DC—Patients with end-stage renal disease require close monitoring of nutrition. However, in patients on hemodialysis, obtaining adequate nutritional status while avoiding fluid overload, hyperphosphatemia, and hyperkalemia is difficult. Researchers in Korea, led by Eunjin Bae, MD, PhD, conducted a retrospective cohort study to examine the clinical significance of serum albumin and other nutritional markers in patients on maintenance hemodialysis. ... Read More »

Patient Reactions to Genetic Testing for ADTKD

Washington, DC—Reactions to a diagnosis of autosomal dominant tubulointerstitial kidney disease (ADTKD) due to UMOD and MUC1 mutations in asymptomatic patients are unknown. Researchers in the United States and Czechia, led by Anthony J. Bleyer, MD at Wake Forest University School of Medicine, Winston-Salem, North Carolina, developed a cross-sectional survey regarding quality of life and genetic testing for individuals who ... Read More »

SZC Improves Potassium Balance in Hyperkalemic Dialysis Patients

Washington, DC—Despite hemodialysis, patients with end-stage renal disease frequently experience predialysis hyperkalemia. The DIALIZE trial (NCT03303521), a phase 3b, randomized, double-blind, placebo-controlled trial, investigated the effect of sodium zirconium cyclosilicate (SZC) on predialysis serum potassium after the long interdialytic interval in dialysis patients with hyperkalemia. Steven Fishbane, MD, and colleagues conducted a post hoc analysis of data from DIALIZE to ... Read More »

Clinical Variables and Timing of RRT Initiation for AKI Patients

Washington, DC—There is no clear consensus on the optimal timing of initiation of dialysis in critically ill patients with acute kidney injury (AKI). Current practice focuses on analyzing survival outcome with arbitrary definitions of early or late start. However, there are few data available on the competing effects of other variables, including clinical comorbidities, dialysis indication, or acuity of illness. ... Read More »

Defibrillator Use in Dialysis Patients: National Cardiovascular Data Registry Report

Washington, DC—Researchers, led by Patrick H. Pun, MD, conducted a retrospective analysis to evaluate trends and the use and in-hospital outcomes of subcutaneous implantable cardioverter defibrillators (S-ICD) compared with transvenous ICDs (TV-ICD) in dialysis patients in the United States. Results of the analysis were reported in a presentation at Kidney Week 2019 in a presentation titled Trends in Use of ... Read More »

Timing of Renal Replacement Therapy Initiation in the ICU

Washington, DC—Increased morbidity and mortality are both associated with acute kidney injury in critically ill patients. The optimal timing of renal replacement therapy (RRT) is unclear and there are no guidelines to aid physicians in decision-making regarding timing of RRT. Mohamad A. Kalot, MD, and colleagues conducted a systematic review and meta-analysis to analyze and synthesize available evidence to guide ... Read More »

Changes in ECG in Acute versus Chronic Hyperkalemia

Washington, DC—Hyperkalemia resulting from kidney failure is associated with life-threatening arrhythmias. Joshua Powell, MD, and colleagues conducted a study to test the hypothesis that patients with chronic hyperkalemia from end-stage renal disease (ESRD) have fewer electrocardiography (ECG) changes and less arrhythmias than patients with acute hyperkalemia from acute kidney injury. Results of the study were reported in an oral presentation ... Read More »

Converting PCR to ACR to Develop CKD Risk Equations

Washington, DC—Staging of chronic kidney disease (CKD) commonly relies on the urine albumin-creatinine ratio (ACR), used in equations to predict the risk of adverse clinical outcomes. However, according to Keiichi Sumida, MD, MPH, PhD, FASN, and colleagues, many trial cohorts and health systems prefer to measure urine protein-creatinine ratio (PCR) rather than ACR. Because those assays measure different components of ... Read More »

Nephrology Care after Acute Kidney Injury

Washington, DC—Patients with acute kidney injury (AKI) are at increased risk for chronic kidney disease, end-stage renal disease, and death. Emily J. See, MBBS, BMedSci, FRACP, and colleagues at Austin Health, Melbourne, Victoria, Australia, conducted a retrospective study to examine the rates of follow-up evaluations of patients with AKI following hospital discharge. Results were reported during a poster session at ... Read More »