Kidney Week 2017

Variations in Use of Best Practices for AKI in Three Connecticut Hospitals

New Orleans—There are associations between acute kidney injury (AKI), common in hospitalized settings, and increased length of stay, morbidity, and mortality. There are no specific therapies for AKI; however, recommended guidelines include measures of best practice that could potentially act as the basis of a standardized set of responses to AKI and the development of an AKI report card. Real-world ... Read More »

No Differences in Outcomes of HLA-Incompatible Living Donor Transplantation versus Other Models

New Orleans—Due to the shortage of available kidneys for transplantation, human leukocyte antigen (HLA)-incompatible living donor kidney transplantation is utilized to increase opportunity for sensitized end-stage renal disease patients. There are inconsistencies in outcomes associated with HLA-incompatible kidney transplantation, however. Data in the United States demonstrated better outcomes for patients undergoing HLA-incompatible kidney transplantation compared with HLA-compatible deceased donor transplantation ... Read More »

Trends in Comorbidities with Hemodialysis and Peritoneal Dialysis

New Orleans—Beginning in 1995, the US Renal Data System has collected data on comorbid conditions in patients receiving hemodialysis or peritoneal dialysis. Rita L. McGill, MD, and colleagues utilized the data to assess the prevalence of various comorbidities in those patient populations over 20 years; trends in both groups were compared. The researchers reported results during a poster session at ... Read More »

Nocturnal Hypertension in Pediatric Transplant Recipients

New Orleans—Pediatric kidney transplant recipients commonly exhibit nocturnal hypertension and non-dipper status during ambulatory blood pressure monitoring, both of which are associated with cardiovascular risk in adults. Christine B. Sethna, MD, and colleagues conducted an open label, blinded end point clinical trial to examine the chronotherapeutic alteration of anti-hypertensive medication on nocturnal hypertension and non-dipper status in a cohort of ... Read More »

Bariatric Surgery Improves Kidney Function via Reduced Systemic Inflammation

New Orleans—Obese patients are at risk for renal disease, including proteinuria, chronic kidney disease (CKD), and progression to end-stage renal disease. Proteinuria can be reduced and renal function can be improved with bariatric surgery; other benefits associated with weight loss include improved blood pressure, improved glucose homeostasis, and reduced systemic inflammation. It is unclear whether the mechanism by which bariatric ... Read More »

Hyponatremia in Newly Diagnosed Dengue Infection

New Orleans—Guidelines from the Pan American Health Organization/World Health Organization issued in 2016 regarding dengue infection and recommendations for the US Centers for Disease Control and Prevention call for high water intake in patients with dengue virus infection. However, there are few data available on the prevalence of hyponatremia in patients newly infected with the virus. Researchers in Argentina, led ... Read More »

Use of Statins in Patients with Non-Dialysis Dependent CKD

New Orleans—Among adults with non-dialysis dependent chronic kidney disease (CKD), morbidity and mortality is strongly associated with cardiovascular disease. The risk of atherosclerotic cardiovascular disease is significantly reduced with the use of statins, especially when combined with ezetimibe, in this patient population. Renal guidelines call for use of statins in all patients with non-dialysis dependent CKD ≥50 years of age ... Read More »

Patient Networks Promote Living Donor Transplantation Conversations

New Orleans—Ideas, attitudes, and behaviors are known to spread within social networks; however, there are few available data on the structure and influence of social networks within the framework of hemodialysis clinics. Avrum Gillespie, MD, and colleagues utilized a survey and observational data to examine the role of patient hemodialysis social networks and discussions of living donor kidney transplantation. Results ... Read More »

BMI and the Risk of Graft and Patient Failure in Kidney Transplantation

New Orleans—Previous studies in kidney transplant recipients with high body mass index (BMI) have yielded conflicting results; some studies reported inferior outcomes compared with patients with lower BMI and others reported superior outcomes in patients with high BMI compared with lower BMI. Whether BMI is a significant independent risk factor for graft failure and patient death in the modern immunosuppressive ... Read More »

Case Report: Patient with Hyponatremia after New Anti-VEGF Therapy

New Orleans—Various chemotherapeutic agents are associated with the development of hyponatremia. Despite good overall outcomes, use of those agents may be limited by severe, symptomatic hyponatremia. During a poster session at Kidney Week 2017, Ari B. Geller, MD, reported a case study of a patient with a history of metastatic renal cell carcinoma with sarcomatoid who presented to the emergency ... Read More »