American Society of Nephrology Kidney Week 2017

Kidney Week 2017 in New Orleans. The American Society of Nephrology Annual Meeting and Scientific Exposition welcomes more than 13,000 kidney professionals from around the world to this premier kidney meeting.

We provide coverage from the meeting on topics such as:

• Rapid Correction of Severe Hyponatremia
• Tolvaptan Improved Hyponatremia in Patient with Melanoma
• Options Education Impacts Modality Choice for ESRD Patients
• Fluid Overload and AKI and Mortality in Influenza Patients
• Hyponatremia and Impaired Cognitive Function: SPRINT Baseline Data
• Early Mortality in Continuous Renal Replacement Therapy
• Case Report: Patient with Hyponatremia after New Anti-VEGF Therapy
• Use of Statins in Patients with Non-Dialysis Dependent CKD
• Hyponatremia in Newly Diagnosed Dengue Infection

View the meeting program here:

Stem Cell Transplant for Refractory Lupus Nephritis

of treating patients with refractory lupus nephritis with autologous hematopoietic stem cell transplantation (ASCT). Twenty-two patients were enrolled in the study between June 2011 and January 2015; inclusion criteria were relapse of refractory lupus nephritis or lack of response to standard immunosuppression therapies. Of the nine men and 13 women in the study cohort, median duration of lupus nephritis was ... Read More »

Genetics of Gout in Patients with CKD

New Orleans—The most common inflammatory arthritis with a strong genetic component worldwide is gout. Patients with chronic kidney disease (CKD) are a high risk for gout, and there are limited data on the genetic risk factors for gout and their interactions with clinical factors in CKD. German researchers performed genome-wide association studies of serum urate and gout in 4941 patients ... Read More »

International Registry of Families with ADTKD Separates Subgroups

New Orleans—The clinical characteristics and diagnostic criteria of various subgroups of patients with autosomal dominant tubulointerstitial kidney disease (ADTKD) are not well defined. A recent international project created a registry of 463 families diagnosed with ADTKD. Index cases were screened for UMOD mutations, followed by MUC1, HNF1B, and REN mutations in families without ADTKD. Results were reported during a poster ... Read More »

Hyperuricemia and Gout Common in Renal Transplant Recipients

New Orleans—As many as 28% of kidney transplant recipients experience hyperuricemia and gout, due, in part, to reduced excretory renal function, intake of diuretic medications, and side effects of immunosuppression drugs. In a poster session at Kidney Week, results of clinical experience with anti-interleukin-1 (IL-1) antibody treatment in three renal transplant recipients with refractory gout arthritis despite various treatment regimens ... Read More »

Emergency Hospitalization Rates for Hemodialysis versus Peritoneal Dialysis Patients

New Orleans—A recent retrospective observational study evaluated 13,078 hospitalizations of patients with end-stage renal disease receiving either hemodialysis (n=1995) or peritoneal dialysis (n=497) therapy to define associations between dialysis modality and emergency hospitalizations for cardiovascular diseases (hemodialysis, 1704; peritoneal dialysis, 261 times) and infectious diseases (excluding infections related to peritoneal dialysis; hemodialysis 970; peritoneal dialysis 132 times) at a single ... Read More »

Body Fat Mass and Risk of Coronary Atherosclerosis

New Orleans—Coronary artery disease (CAD) is one of the most common cardiovascular diseases; CAD is associated with mortality in patients with chronic kidney disease (CKD). Beginning at the early stages of CKD, several known cardiovascular disease risk factors, such as obesity, are seen in that patient population. A recent cross-sectional study aimed to assess the presence of atherosclerosis and possible ... Read More »

Retention of Uric Acid Transporters and Hyperuricemia in ADTKD

New Orleans—Uromodulin (UMOD) mutations cause autosomal dominant tubulointerstitial kidney disease (ADTKD). Patients with ADTKD-UMOD generally show hyperuricemia in childhood and progression to renal failure in the course of the disease. UMOD has been localized to the proximal tubulus and uric acid transponders have been localized to the distal proximal tubulus. UMOD WT interacts with the uric acid transporters ABCG2, URAT1, ... Read More »

Predicting Renal Survival in Diabetic Nephropathy

New Orleans—The ability to predict progression of renal disease in patients with diabetes is limited, despite the identification of risk factors that include glycemic control, blood pressure, and albuminuria. Researchers conducted a study to examine the relationship between the Renal Pathology Society pathologic classification system score and progression of diabetic renal disease. Of 394 biopsies performed at St. Michael’s Hospital, ... Read More »

Pathways Associated with Hyperuricemia in Hispanic Children

New Orleans—Hyperuricemia in children is known to be predictive of hypertension in adulthood. Researchers studied 260 Hispanic children (130 with hyperuricemia and 130 without hyperuricemia) from the Viva La Familia study to identify urinary metabolites and pathways associated with hyperuricemia. A total of 703 metabolites were identified; of those, 377 were significantly different between the two groups. Key differences were ... Read More »

Pegloticase Decreases in MAP in Patients with Chronic Gout

New Orleans—In an analysis of results from randomized clinical trials of pegloticase, researchers examined the impact of persistent, very low levels of serum uric acid on blood pressure in patients with chronic refractory gout. The analysis included data on 29 responders whose mean arterial pressure (MAP) at baseline was 94.9 mm Hg. Throughout the 6-month trial, there were significant reductions ... Read More »