Conference Coverage

KDIGO Recommendations for Slowing CKD Progression

New Orleans—Several measures for prevention of progression of chronic kidney disease (CKD) were included in 2012 recommendations in guidelines from Kidney Disease Improving Global Outcomes. The measures include blood pressure control, use of renin-angiotensin system inhibitors (RASi), and dietary advice. There are few data on whether the recommendations are followed in current nephrology practice. Benedict Stengel, MD, and colleagues recently ... Read More »

AKI Common in Patients Treated for Cancer

New Orleans—There is an increased risk for acute kidney (AKI) among patients being treated for cancer; however, there have been limited studies on the incidence of AKI and risk factors in the current treatment era. Researchers in Canada conducted a population-level cohort study using linked administrative databases that included all patients who initiated systemic therapy, including chemotherapy and targeted agents, ... Read More »

Effectiveness of Tolvaptan in Patients with ADPKD

New Orleans—Researchers in Japan, led by Shigeo Horie, MD, recently conducted a study designed to examine the influence of genetic factors on the efficacy of treatment with tolvaptan in patients with approved autosomal dominant polycystic kidney disease (ADPKD). They reported results during a poster session at Kidney Week 2017 in a poster titled Pharmacogenomics of Tolvaptan’s Inhibitory Effect on Kidney ... Read More »

Trends in Comorbidities with Hemodialysis and Peritoneal Dialysis

New Orleans—Beginning in 1995, the US Renal Data System has collected data on comorbid conditions in patients receiving hemodialysis or peritoneal dialysis. Rita L. McGill, MD, and colleagues utilized the data to assess the prevalence of various comorbidities in those patient populations over 20 years; trends in both groups were compared. The researchers reported results during a poster session at ... Read More »

Nocturnal Hypertension in Pediatric Transplant Recipients

New Orleans—Pediatric kidney transplant recipients commonly exhibit nocturnal hypertension and non-dipper status during ambulatory blood pressure monitoring, both of which are associated with cardiovascular risk in adults. Christine B. Sethna, MD, and colleagues conducted an open label, blinded end point clinical trial to examine the chronotherapeutic alteration of anti-hypertensive medication on nocturnal hypertension and non-dipper status in a cohort of ... Read More »

Bariatric Surgery Improves Kidney Function via Reduced Systemic Inflammation

New Orleans—Obese patients are at risk for renal disease, including proteinuria, chronic kidney disease (CKD), and progression to end-stage renal disease. Proteinuria can be reduced and renal function can be improved with bariatric surgery; other benefits associated with weight loss include improved blood pressure, improved glucose homeostasis, and reduced systemic inflammation. It is unclear whether the mechanism by which bariatric ... Read More »

Hyponatremia in Newly Diagnosed Dengue Infection

New Orleans—Guidelines from the Pan American Health Organization/World Health Organization issued in 2016 regarding dengue infection and recommendations for the US Centers for Disease Control and Prevention call for high water intake in patients with dengue virus infection. However, there are few data available on the prevalence of hyponatremia in patients newly infected with the virus. Researchers in Argentina, led ... Read More »

Use of Statins in Patients with Non-Dialysis Dependent CKD

New Orleans—Among adults with non-dialysis dependent chronic kidney disease (CKD), morbidity and mortality is strongly associated with cardiovascular disease. The risk of atherosclerotic cardiovascular disease is significantly reduced with the use of statins, especially when combined with ezetimibe, in this patient population. Renal guidelines call for use of statins in all patients with non-dialysis dependent CKD ≥50 years of age ... Read More »

Patient Networks Promote Living Donor Transplantation Conversations

New Orleans—Ideas, attitudes, and behaviors are known to spread within social networks; however, there are few available data on the structure and influence of social networks within the framework of hemodialysis clinics. Avrum Gillespie, MD, and colleagues utilized a survey and observational data to examine the role of patient hemodialysis social networks and discussions of living donor kidney transplantation. Results ... Read More »

BMI and the Risk of Graft and Patient Failure in Kidney Transplantation

New Orleans—Previous studies in kidney transplant recipients with high body mass index (BMI) have yielded conflicting results; some studies reported inferior outcomes compared with patients with lower BMI and others reported superior outcomes in patients with high BMI compared with lower BMI. Whether BMI is a significant independent risk factor for graft failure and patient death in the modern immunosuppressive ... Read More »