Conference Coverage

Variations in Use of Best Practices for AKI in Three Connecticut Hospitals

New Orleans—There are associations between acute kidney injury (AKI), common in hospitalized settings, and increased length of stay, morbidity, and mortality. There are no specific therapies for AKI; however, recommended guidelines include measures of best practice that could potentially act as the basis of a standardized set of responses to AKI and the development of an AKI report card. Real-world ... Read More »

No Differences in Outcomes of HLA-Incompatible Living Donor Transplantation versus Other Models

New Orleans—Due to the shortage of available kidneys for transplantation, human leukocyte antigen (HLA)-incompatible living donor kidney transplantation is utilized to increase opportunity for sensitized end-stage renal disease patients. There are inconsistencies in outcomes associated with HLA-incompatible kidney transplantation, however. Data in the United States demonstrated better outcomes for patients undergoing HLA-incompatible kidney transplantation compared with HLA-compatible deceased donor transplantation ... Read More »

Gender-Related Differences in Hypoglycemia with Glucose-Lowering Treatment

New Orleans—Treatment recommendations for lowering glucose vary by chronic kidney disease (CKD) stage. Despite possible differences in efficacy, there are no differences in treatment recommendations by gender, raising the possibility of differences in glucose control and hypoglycemia by gender. In a French study conducted by Marie Metzger, MD, and colleagues, 3033 patients with CKD stages 3 to 5 were recruited; ... Read More »

Continuation of Loop Diuretics Beneficial in First Year after Dialysis Initiation

New Orleans—Patients with non-dialysis dependent chronic kidney disease are often managed with use of loop diuretics. Upon initiation of hemodialysis, loop diuretics are often discontinued, despite potential benefits of augmented urine output. Researchers, led by Steven M. Brunelli, MD, recently conducted an analysis designed to examine the association between the early decision to continue versus discontinue loop diuretics at start ... Read More »

Survival with Intensive Home Hemodialysis Similar to Deceased Donor Kidney Transplantation

New Orleans—For patients with end-stage renal disease (ESRD), the treatment of choice is kidney transplantation; however, there is a shortage of available kidney donors. Results of a previous study in Canada suggested that intensive home hemodialysis had similar survival rates to that of recipients of deceased donor kidney transplantation. Angie G. Nishio-Luca, MD, and colleagues conducted a study in the ... Read More »

Statin Therapy Reduces Occurrence of AKI after Angiography

New Orleans—The diagnosis and treatment of cardiovascular diseases is often complicated by the presence of acute kidney injury (AKI). Previous studies have demonstrated a significant decrease in the occurrence of AKI when patients were treated with statin therapy prior to coronary angiography and/or intervention; however, the association between pretreatment statin therapy and the occurrence of AKI in patients with peripheral ... Read More »

Spousal Donor Kidney Transplantation Outcomes

New Orleans—Even with poor histocompatibility and older age, it is known that the rate of graft survival in transplantations involving spousal kidney donation is similar to that of living related donor kidney transplantation. Marriage is the distinctive feature in spousal kidney donation (SKD) and other living unrelated kidney donation. Married people live longer and have better health than single people ... Read More »

Donor-Recipient Size Mismatch and Rates of Graft Survival

New Orleans—Poorer kidney graft survival is associated with advanced donor age, recipient age, and donor-recipient size mismatch. However, there are few available data on the interaction among these variables. Researchers in Canada conducted a retrospective cohort study designed to examine those interactions. Fanny Lepeytre, MD, reported results of the study during a poster session at Kidney Week 2017 in a ... Read More »

KDIGO Recommendations for Slowing CKD Progression

New Orleans—Several measures for prevention of progression of chronic kidney disease (CKD) were included in 2012 recommendations in guidelines from Kidney Disease Improving Global Outcomes. The measures include blood pressure control, use of renin-angiotensin system inhibitors (RASi), and dietary advice. There are few data on whether the recommendations are followed in current nephrology practice. Benedict Stengel, MD, and colleagues recently ... Read More »

AKI Common in Patients Treated for Cancer

New Orleans—There is an increased risk for acute kidney (AKI) among patients being treated for cancer; however, there have been limited studies on the incidence of AKI and risk factors in the current treatment era. Researchers in Canada conducted a population-level cohort study using linked administrative databases that included all patients who initiated systemic therapy, including chemotherapy and targeted agents, ... Read More »