American Society of Nephrology

Kidney Week 2017 in New Orleans. The American Society of Nephrology Annual Meeting and Scientific Exposition welcomes more than 13,000 kidney professionals from around the world to this premier kidney meeting.

We provide coverage from the meeting on topics such as:

• Rapid Correction of Severe Hyponatremia
• Tolvaptan Improved Hyponatremia in Patient with Melanoma
• Options Education Impacts Modality Choice for ESRD Patients
• Fluid Overload and AKI and Mortality in Influenza Patients
• Hyponatremia and Impaired Cognitive Function: SPRINT Baseline Data
• Early Mortality in Continuous Renal Replacement Therapy
• Case Report: Patient with Hyponatremia after New Anti-VEGF Therapy
• Use of Statins in Patients with Non-Dialysis Dependent CKD
• Hyponatremia in Newly Diagnosed Dengue Infection

View the meeting program here:

https://www.asn-online.org/education/kidneyweek/2017/meeting-overview.aspx

Identifying Rapid Progression in Patients with ADPKD

New Orleans—The most frequently inherited kidney disease is autosomal dominant polycystic kidney disease (ADPKD). The progressive cyst growth associated with ADPKD, combined with interstitial damage, causes progressive kidney failure; there is wide variation of the severity of ADPKD among this patient population. The European Medicines Agency has approved tolvaptan for adults with CKD stage 1 to 3 at baseline who ... Read More »

Predicting Hyponatremia from Electronic Medical Records

New Orleans—In both hospitalized and ambulatory patients, hyponatremia is associated with increased morbidity and mortality. Utilizing electronic medical records (EMRs) to identify patients at high risk for hyponatremia may have significant impact on patient outcomes, according to Young-Il Jo, MD, and Sug kyun Shin, MD. Identification of high-risk patients can also serve to support clinical decision making the management of ... Read More »

Biomarkers for Early Diagnosis of AKI in Critically Ill Patients

New Orleans—Hospitalized patients may experience acute kidney injury (AKI), a condition that is more common among patients in the intensive care unit (ICU). Serum creatinine measurement can be used to assess AKI; however, according to Luana A. Pedroso, MD, and colleagues, serum creatinine is a poor and delayed marker of AKI. In recent decades, new circulating and urinary biomarkers have ... Read More »

Pathways and Biomarkers for Progression of Diabetic Kidney Disease

New Orleans—The leading cause of end-stage renal disease (ESRD) is diabetic kidney disease. According to researchers, understanding of molecular pathways involved in the initiation and progression of diabetic kidney disease facilitates development of biomarkers and identification of drug targets. Skander Mulder, MD, and colleagues conducted a study designed to identify molecular pathways associated with progressive loss of kidney function in ... Read More »

Early Mortality in Continuous Renal Replacement Therapy

New Orleans—In patients with acute kidney injury (AKI) who are hemodynamically unstable, the treatment modality of choice is continuous renal replacement therapy (CRRT). However, according to researchers, the mortality rate in AKI in intensive care units is high despite the use of CRRT. Haewon Lee, MD, and colleagues in the Republic of Korea conducted a retrospective observational study designed to ... Read More »

Hyponatremia and Impaired Cognitive Function: SPRINT Baseline Data

New Orleans—There are limited data exploring the association between hyponatremia and reversible cognitive impairment. Researchers, led by Daniel E. Weiner, MD, recently conducted an analysis of baseline data from the SPRINT (Systolic Blood Pressure Intervention) cognition substudy (SPRINT-MIND) to examine the relationship between serum sodium concentration and cognitive function. They reported results during a poster session at Kidney Week 2017 ... Read More »

Size Mismatch in Pediatric Living Donor Kidney Transplantation

New Orleans—Previous studies have demonstrated an association between small donor body size in relation to recipient body size and increased risk of graft loss following kidney transplantation. There are few data, however, on this relationship in young children undergoing living donor kidney transplantation, a patient population with a greater possibility of size mismatch. Heather L. Wasik, MD, and colleagues at ... Read More »

Options Education Impacts Modality Choice for ESRD Patients

New Orleans—Patients with chronic kidney disease making decisions regarding options for renal replacement therapy (RRT) may be helped with the use of education programs on dialysis; however, there are few data on the impact of educational programs on modality choice. Yue Jiao, MD, and colleagues at Fresenius Medical Care North America (Waltham, MA) conducted an analysis designed to examine the ... Read More »

Tolvaptan Improved Hyponatremia in Patient with Melanoma

New Orleans—The 10-year survival rate for patients with metastatic melanoma is <10%. The majority of patients are treated with systemic therapy, and there are associations between immunotherapeutic agents and durable response in some patients. In 1998, the FDA approved high dose interleukin-2 (IL-2) for treatment of metastatic melanoma. Common adverse effects include fever, chills, hypotension, cardiac arrhythmias, oliguria, volume overload, ... Read More »

Rapid Correction of Severe Hyponatremia

New Orleans—In patients with severe hyponatremia, rapid correction of serum sodium can result in serious adverse clinical consequences, including central pontine myelinolysis (CPM). There are few available data on the clinical risk factors associated with rapid correction of hyponatremia and on the incidence of CPM among patients with severe hyponatremia. Jason C. George, MD, and colleagues utilized data on 1352 ... Read More »