Author Archives: Shane Whitney

Fluid Management Quality Improvement Project Using Relative Blood Volume Monitoring

San Diego—Patients receiving hemodialysis at 20 Renal Research Institute clinics participated in a 1-year fluid management quality improvement (QI) project utilizing relative blood volume monitoring (RBV-M). Paul Balter, MD, and colleagues conducted a retrospective database analysis to examine changes in body weight and blood pressure in the participating patients. Results of the analysis were reported during a poster session at ... Read More »

TRC101 to Treat Patients with Chronic Kidney Disease and Metabolic Acidosis

San Diego—The risk of chronic kidney disease (CKD) progression is increased in patients with metabolic acidosis, and metabolic acidosis adversely affects muscle and bone. TRC101, a non-absorbed , sodium-free polymeric drug that selectively binds and removes hydrochloric acid from the gastrointestinal tract, is being developed to treat metabolic acidosis and slow the progression of CKD. Donald E. Wesson, MD, MBA, ... Read More »

RenalytixAI Developing AI-Enabled Clinical Diagnostic Products for Kidney Disease

RenalytixAI, a developer of artificial intelligence-enabled clinical diagnostics for kidney disease, has raised $29 million to support the development and commercialization of two product categories for the early detection of kidney disease and accurate management of kidney transplant rejection. The launch of the first product, KidneyIntelX™, is planned for 2019; the launch will be conducted in collaboration with the Icahn ... Read More »

AKI Subphenotypes and Response to Vasopressin Therapy

American Journal of Respiratory and Critical Care Medicine. doi.org/10.1164/rccm.201807-13460C Results of a study designed to identify and test whether acute kidney injury (AKI) subphenotypes have prognostic and therapeutic implications were reported by Pavan K. Bhatraju, MD, and colleagues. Latent class analysis methodology was applied independently in two critically ill populations (discovery, n=794, and replication, n=425) with AKI. AKI subphenotypes were ... Read More »

From the Field: Patient Payments Part 2

Last issue I mentioned that a social worker commented to me that she wishes providers would stop trying to collect from patients. She said providers “make enough money” and wondered why they feel the need to collect from patients who cannot afford their large coinsurances and deductibles. She pointed out that increasing pressure on patients to pay for coinsurances and ... Read More »

From the Chair: Nephrologists are Among the Most Happy Subspecialists in the US

Ajay K. Singh Recent data on happiness among nephrologists should be a reason to celebrate the New Year. In the 2019 Medscape Physician Lifestyle and Happiness Report1 for “happiness outside work,” 55% of nephrologists are happiest outside work (the best ratings were for rheumatologists at 65% and the worst was for neurologists at 45%). If that were not enough, 65% ... Read More »

New Hypertension Targets Improve Patient and Graft Survival

San Diego—Utilizing data from SPRINT (Systolic Blood pressure Intervention Trial), American national guidelines reduced the blood pressure goal from 140.90 mm Hg to 130/80 mm HG for subjects with increased cardiovascular risk, including patients with chronic kidney disease (CKD). There are few data available on whether renal transplant recipients benefit from the reduced blood pressure goals. Nikolaos Pagonas, MD, and ... Read More »

Prognostic Importance of Atrial Fibrillation in Kidney Transplant Recipients

Atrial fibrillation (AF) affects three to six million people in the United States, and nearly 30 million people worldwide. AF is associated with higher risk of mortality and adverse cardiovascular events including stroke. Among patients with end-stage renal disease (ESRD), the prevalence of AF is particularly high compared to the general population. In addition, the 1-year mortality risk of patients ... Read More »

Variations in Duration of Kidney Transplant Donor Evaluation

Among patients with kidney failure, kidney transplantation is associated with improved survival, better quality of life, and reduced healthcare costs compared with dialysis therapy. Living donor transplantation provides advantages over deceased donor transplantation, including superior rates of graft and patient survival and shorter time to transplantation. When potential living donors contact a transplantation center, the evaluation process begins with a ... Read More »