Author Archives: Kelly Gavin

Predictors for Acute Kidney Injury Following Cardiac Surgery

Patients undergoing cardiac surgery may experience acute kidney injury (AKI), a common and serious complication. Nearly one in five patients undergoing cardiac surgery experience mild AKI, which is associated with a 19-fold increase in short-term mortality. Severe AKI, defined as requiring renal replacement therapy, occurs in 2% of patients; in those patients, mortality rates approach 20%. In addition to increased ... Read More »

Prediction Tool for Mortality Risk among Older Adults Includes Seven Variables

Maintenance dialysis is the most commonly utilized modality for renal replacement therapy among older adults. In Canada, the proportion of incident dialysis patients ≥65 years of age rose from 41.8% in 1994 to 53.5% in 2013. Older adults on dialysis are at increased risk for poor outcomes, including death; the mortality rate in that patient population is as much as ... Read More »

A Pilot Trial to Assess the Effectiveness of Screening for CKD among High Risk Patients

Currently, the value of screening for chronic kidney disease (CKD) is uncertain. Previous evidence suggests that in certain high-risk groups, screening may be cost-effective in reducing the burden of complications associated with CKD. More than 20 million adults in the United States are affected by CKD, defined by either of two readily available clinical tests: estimated glomerular filtration rate <60 ... Read More »

Utilization of rhGH Therapy in Children with CKD and Growth Impairment Varies

Despite advances in care for children with chronic kidney disease (CKD), growth impairment remains common in the population of pediatric CKD patients. Data from the North American Pediatric Renal Trials and Collaborative Studies CKD registry show that 36.9% had height standard deviation scores (SDS) <–1.88 at time of enrollment. In a recent study in North America among children with mild ... Read More »

Trends in Comorbidities with Hemodialysis and Peritoneal Dialysis

New Orleans—Beginning in 1995, the US Renal Data System has collected data on comorbid conditions in patients receiving hemodialysis or peritoneal dialysis. Rita L. McGill, MD, and colleagues utilized the data to assess the prevalence of various comorbidities in those patient populations over 20 years; trends in both groups were compared. The researchers reported results during a poster session at ... Read More »

Nocturnal Hypertension in Pediatric Transplant Recipients

New Orleans—Pediatric kidney transplant recipients commonly exhibit nocturnal hypertension and non-dipper status during ambulatory blood pressure monitoring, both of which are associated with cardiovascular risk in adults. Christine B. Sethna, MD, and colleagues conducted an open label, blinded end point clinical trial to examine the chronotherapeutic alteration of anti-hypertensive medication on nocturnal hypertension and non-dipper status in a cohort of ... Read More »

Bariatric Surgery Improves Kidney Function via Reduced Systemic Inflammation

New Orleans—Obese patients are at risk for renal disease, including proteinuria, chronic kidney disease (CKD), and progression to end-stage renal disease. Proteinuria can be reduced and renal function can be improved with bariatric surgery; other benefits associated with weight loss include improved blood pressure, improved glucose homeostasis, and reduced systemic inflammation. It is unclear whether the mechanism by which bariatric ... Read More »

Hyponatremia in Newly Diagnosed Dengue Infection

New Orleans—Guidelines from the Pan American Health Organization/World Health Organization issued in 2016 regarding dengue infection and recommendations for the US Centers for Disease Control and Prevention call for high water intake in patients with dengue virus infection. However, there are few data available on the prevalence of hyponatremia in patients newly infected with the virus. Researchers in Argentina, led ... Read More »

Use of Statins in Patients with Non-Dialysis Dependent CKD

New Orleans—Among adults with non-dialysis dependent chronic kidney disease (CKD), morbidity and mortality is strongly associated with cardiovascular disease. The risk of atherosclerotic cardiovascular disease is significantly reduced with the use of statins, especially when combined with ezetimibe, in this patient population. Renal guidelines call for use of statins in all patients with non-dialysis dependent CKD ≥50 years of age ... Read More »

Patient Networks Promote Living Donor Transplantation Conversations

New Orleans—Ideas, attitudes, and behaviors are known to spread within social networks; however, there are few available data on the structure and influence of social networks within the framework of hemodialysis clinics. Avrum Gillespie, MD, and colleagues utilized a survey and observational data to examine the role of patient hemodialysis social networks and discussions of living donor kidney transplantation. Results ... Read More »