Author Archives: Kerri Fitzgerald

Warfarin Use in Hemodialysis Patients with Atrial Fibrillation

Warfarin use in hemodialysis patients with incident atrial fibrillation (AF) was marginally associated with reduced risk of ischemic stroke in a study conducted recently by Jenny I. Shen, MD, MSc, and colleagues. The researchers reported results of the retrospective observational cohort study in the American Journal of Kidney Diseases [2015;66(4):677-688]. AF affects an estimated 2.7 million Americans. Independent risk factors ... Read More »

Physical Functional Status Associated with Improved Survival Rate Among Transplant Recipients

For patients wait-listed for a kidney transplant, functional status may help in determining which patients will derive a benefit from transplantation compared with continued maintenance dialysis therapy. That was among the findings of a retrospective cohort study conducted recently by Peter P. Reese, MD, MSCE, and colleagues [Am J Kidney Dis. 2015;66(5):837-845]. Healthcare providers face continuing challenges in assessing the ... Read More »

Sucroferric Oxyhydroxide Reduces Pill Burden Compared to Sevelamer

San Diego—In a study conducted among Japanese hemodialysis patients with hyperphosphatemia, PA 21 (sucroferric oxyhydroxide [SFOH]) showed a significant serum phosphorus reduction compared with sevelamer hydrochloride (HCI). That was among the findings of a randomized, open-label, parallel-group, multicenter, active-controlled phase 3 study reported during a poster session at Kidney Week 2015. Fumihiko Koiwa, MD, PhD, and colleagues reported the study ... Read More »

Risk of AKI in Females Related to Baseline Health

Dallas—Up to 30% of patients undergoing cardiac surgery experience acute kidney injury (AKI). AKI is associated with an increased risk of infection and extended hospital length-of-stay. Further, AKI-associated mortality ranges from 15% to 30%. Previous intensive care unit studies have found a lower risk of AKI in women compared with men. However, following cardiac surgery, the risk of AKI in ... Read More »

CAD Management in Patients with Chronic Kidney Disease

Dallas—Researchers at Staten Island University Hospital, Staten Island, New York, recently conducted a retrospective cohort study to provide a basis for the management of coronary artery disease (CAD) in patients with chronic kidney disease (CKD). Marc Saad, MD, and colleagues reported results of the study during a poster session at the NFK 2015 Spring Clinical Meetings. The poster was titled ... Read More »

Risk of Hemorrhage Higher in Warfarin Users with CKD

Patients with lower estimated glomerular filtration rates (eGFRs) have differentially higher hemorrhage risk at international normalized ratio (INR) ≥4. That was among the findings of a prospective cohort study conducted recently by Nita A. Limdi, PharmD, PhD, and colleagues. The researchers reported their findings in the American Journal of Kidney Diseases [2015;65(5):701-709]. Warfarin, the most commonly prescribed oral anticoagulant, presents ... Read More »

Algorithm for Prediction of AVF Failure to Mature

Dallas—Current practice guidelines from the National Kidney Foundation’s Kidney Disease Outcomes Quality initiative and the Fistula First Initiative recommend the use of arteriovenous fistulas (AVFs) over the use of other capsular access options. However, according to Davis Bradford and Michael Allon of the University of Alabama School of Medicine, Birmingham, clinical decision making regarding the optimal vascular access type should ... Read More »

Infection-Related Hospitalizations and 30-Day Readmissions among HD Patients

Among patients receiving in-center hemodialysis, there are significant clinical complications associated with hospitalizations for infections. That was the primary finding of a retrospective cohort study conduced recently by Lorien S. Dalrymple, MD, MPH, and colleagues. The researchers reported study results in the American Journal of Kidney Diseases [2015;65(5):754-762]. In patients receiving hemodialysis, infection accounts for nearly one-fourth of hospitalizations, according ... Read More »

Cost-Effectiveness of Biocompatible Solutions in Peritoneal Dialysis

For patients receiving peritoneal dialysis (PD) therapy, biocompatible solution may offer a cost-effective alternative to standard solutions. That was the primary finding of a secondary economic evaluation of a randomized controlled trial conducted recently by Kirsten Howard, PhD, and colleagues. The researchers reported their results in the American Journal of Kidney Diseases [2015;65(5):773-779]. PD is a home-based model that more ... Read More »

CKD Stage Has Impact on Hospital Costs in Moderate-to-Severe CKD

Renal replacement therapy (RRT), major vascular events, and deaths, both vascular and non-vascular, are the key determinants of costs of hospital care in the United Kingdom for patients with moderate-to-severe chronic kidney disease (CKD). That was the primary finding of a secondary analysis of data from the SHARP (Study of Heart and Renal Protection) trial conducted recently by Seamus Kent, ... Read More »