Author Archives: Kerri Fitzgerald

Review and Meta-Analysis to Assess Renal Outcomes with Intensive Blood Pressure Control

Patients with chronic kidney disease face increased risk of diabetes, cardiovascular morbidity, and mortality; nondiabetic CKD accounts for most of the incidence worldwide. Hypertension is strongly associated with the development of progression of nondiabetic CKD, and control of blood pressure can decrease the risk of decline in renal function and cardiovascular mortality. However, according to Wan-Chuan Tsai, MD, and colleagues ... Read More »

Peritoneal Dialysis Compared with Hemodialysis in Infants Younger than One Year

Pediatric nephrologists face significant challenges in managing infants requiring maintenance dialysis. Factors such as difficulties feeding and maintaining fluid balance, growth failure, increased risk of infection, and possible comorbid conditions contribute to the management hurdles in children younger than 1 year. Due in part to these challenges, infants with kidney failure on maintenance dialysis have higher mortality rates than older ... Read More »

Three versus Four Daily Exchanges in Continuous Ambulatory Peritoneal Dialysis and Residual Kidney Function

Survival and quality of life for patients on dialysis are associated with residual kidney function. The preferred modality for preservation of residual kidney function is peritoneal dialysis, according to Hao Yan, MD, and colleagues in the department of nephrology, Renji Hospital, School of Medicine, Shanghai Jiaotong University and Shanghai Center for Peritoneal Dialysis Research, Shanghai, China. The preservation of residual ... Read More »

Appropriateness of Antibiotics Prescribed to Hemodialysis Patients

Worldwide, mortality and hospitalization in patients receiving maintenance hemodialysis are due, in part, to infection. Individuals in this patient population are also at risk of infections caused by multi-drug resistant organisms. Inappropriate use of antibiotics is a driver for the acceleration of antimicrobial resistance, giving rise to global efforts to optimize antimicrobial use. Patients in Australia receive maintenance hemodialysis in ... Read More »

Kidney Injuries at a Level 1 Trauma Center

Orlando—Elmhurst Hospital Center at the Icahn School of Medicine in Queens, New York, is a level 1 trauma center. Approximately 3% of all trauma admissions at the center are renal trauma cases; among patients who sustain abdominal trauma, as many as 10% of trauma admissions involve renal trauma. Researchers at the center, led by Jayaramakrishna Depa, MD, conducted a retrospective ... Read More »

From the Chair: Home Dialysis Takes a Big Step

Ajay K. Singh, MBBS, FRCP, MBA Brigham and Women’s Hospital and Harvard Medical School  Boston, Massachusetts From the early days of hemodialysis, many, including the late Dr. Bernard Scribner at the University of Seattle, worked tirelessly to promote home hemodialysis. In the early 1970s, the use of home hemodialysis peaked, with nearly 40% of all patients in the United States ... Read More »

Hemoglobin A1c Level Control and Risk of ESRD and Mortality in Patients with CKD

Patients with both diabetes and chronic kidney disease (CKD) are at increased risk for death, compared with those with diabetes or CKD alone. Diabetic kidney disease is increasing in prevalence; diabetic nephropathy is the leading cause of end-stage renal disease (ESRD). The ideal level of glycated hemoglobin (hemoglobin A1c [HbA1c]) has not been positively established; results of some clinical trials ... Read More »

Biomarkers of Kidney Injury and Repair Measured in Marathon Runners

In 2014, a record number of individuals in the United States competed in a marathon; the increase in marathon participation to 550,600 has subsequently increased the need to more closely examine the relationship between marathon running and kidney injury. Because runners are generally seen as healthy athletes with trained physiology to tolerate high states of energy expenditure, the relationship between ... Read More »

Predialysis Systolic Blood Pressure and Risk of All-Cause Mortality Postdialysis

The incidence of end-stage renal disease (ESRD) among individuals with chronic kidney disease (CKD) is high, despite advances in the understanding of CKD progression. Patients with CKD not dependent on dialysis who transition to ESRD have the highest mortality within the first few months following the transition to dialysis therapy. Those patients also have exceptionally high healthcare costs and burden. ... Read More »