Author Archives: Kerri Fitzgerald

Three versus Four Daily Exchanges in Continuous Ambulatory Peritoneal Dialysis and Residual Kidney Function

Survival and quality of life for patients on dialysis are associated with residual kidney function. The preferred modality for preservation of residual kidney function is peritoneal dialysis, according to Hao Yan, MD, and colleagues in the department of nephrology, Renji Hospital, School of Medicine, Shanghai Jiaotong University and Shanghai Center for Peritoneal Dialysis Research, Shanghai, China. The preservation of residual ... Read More »

Appropriateness of Antibiotics Prescribed to Hemodialysis Patients

Worldwide, mortality and hospitalization in patients receiving maintenance hemodialysis are due, in part, to infection. Individuals in this patient population are also at risk of infections caused by multi-drug resistant organisms. Inappropriate use of antibiotics is a driver for the acceleration of antimicrobial resistance, giving rise to global efforts to optimize antimicrobial use. Patients in Australia receive maintenance hemodialysis in ... Read More »

Kidney Injuries at a Level 1 Trauma Center

Orlando—Elmhurst Hospital Center at the Icahn School of Medicine in Queens, New York, is a level 1 trauma center. Approximately 3% of all trauma admissions at the center are renal trauma cases; among patients who sustain abdominal trauma, as many as 10% of trauma admissions involve renal trauma. Researchers at the center, led by Jayaramakrishna Depa, MD, conducted a retrospective ... Read More »

From the Chair: Home Dialysis Takes a Big Step

Ajay K. Singh, MBBS, FRCP, MBA Brigham and Women’s Hospital and Harvard Medical School  Boston, Massachusetts From the early days of hemodialysis, many, including the late Dr. Bernard Scribner at the University of Seattle, worked tirelessly to promote home hemodialysis. In the early 1970s, the use of home hemodialysis peaked, with nearly 40% of all patients in the United States ... Read More »

Hemoglobin A1c Level Control and Risk of ESRD and Mortality in Patients with CKD

Patients with both diabetes and chronic kidney disease (CKD) are at increased risk for death, compared with those with diabetes or CKD alone. Diabetic kidney disease is increasing in prevalence; diabetic nephropathy is the leading cause of end-stage renal disease (ESRD). The ideal level of glycated hemoglobin (hemoglobin A1c [HbA1c]) has not been positively established; results of some clinical trials ... Read More »

Biomarkers of Kidney Injury and Repair Measured in Marathon Runners

In 2014, a record number of individuals in the United States competed in a marathon; the increase in marathon participation to 550,600 has subsequently increased the need to more closely examine the relationship between marathon running and kidney injury. Because runners are generally seen as healthy athletes with trained physiology to tolerate high states of energy expenditure, the relationship between ... Read More »

Predialysis Systolic Blood Pressure and Risk of All-Cause Mortality Postdialysis

The incidence of end-stage renal disease (ESRD) among individuals with chronic kidney disease (CKD) is high, despite advances in the understanding of CKD progression. Patients with CKD not dependent on dialysis who transition to ESRD have the highest mortality within the first few months following the transition to dialysis therapy. Those patients also have exceptionally high healthcare costs and burden. ... Read More »

Treating Hypertension in Transplant Recipients: Chlorthalidone versus Amlodipine

In kidney transplantation recipients, hypertension following the transplant has been shown to be an independent risk factor for transplant failure. Hypertension after transplantation is also associated with increased risk for cardiovascular disease and mortality. Contributors involved in development of hypertension after transplant include donor, recipient, and transplantation factors. Patients treated with calcineurin inhibitors (CNIs) have been shown to have increased ... Read More »

Cognitive Impairment Among Kidney Transplant Recipients

As many as 50% to 87% of patients on maintenance dialysis experience cognitive impairment, influencing quality of life, employment rates, adherence to treatment, hospital admissions, health care costs, morbidity, and mortality. Kidney transplantation offers advantages in quality of life and survival over dialysis, but kidney transplant recipients have several risk factors for cognitive impairment, including comorbid illness, depression, and lower ... Read More »